ZP is attending FARAON-2022

CONFERENCE DETAILS

Recent developments in Advanced Functional Materials have paved the way for innovation and novel applications to meet the growing energy demand and environmental challenges. FARAON-2022 provides a great platform to promote the breakthrough research works accomplished in the past decade and publish novel & potential advanced research works focussing on energy, environment, and biomedical applications from the branches of Physics, Chemistry, and Biological Sciences. The program is initiated as a joint collaboration between India and Norway to integrate and promote the interdisciplinary activity between both nations in the field of science and to extend the collaboration with international researchers from academia and industries. FARAON-2022 aims to provide a platform for the young researchers to present, share, and discuss the latest and upcoming developments in Advanced Functional Materials with wide networking.

On this page we provide some demo files from: PalmSens, Autolab and CH Instruments, so you can practise uploading software up to Djuli.

Djuli is a multi-functional Scientific and Cloud Database, whose applications include: the storage, analysis and sharing of electrochemical data.

PalmSens_AnaPot Data

CH Instruments Data

This week ZP has received some new designs into the ZP Fashion Store.

Zimmer and Peacock will be providing live demonstration at ETADS22 from 12 PM to 1 PM IST (India) on Friday 22 January 2022.

Abstract 

Join us in early 2022 for this Three day International E-Conference. For in this year 2021, RTNPRA-21 Completed in successful and it have been the forefront of Natural Products Chemistry and overall chemical applications are focused.

We invite you to join us to discuss the topic of Electro analytical techniques and its applications in sensors and make your contribution to this cutting-edge discussion alongside in this field.

This meeting is for established and early career professors, scientists, post-graduate students and industrial researchers interested in the key aspects of Electro analytical techniques and how they can drive forward many areas of science including the development of sensors. The subject of Electro analytical techniques is one of the most intellectually-attractive and experimentally-demanding frontiers in modern chemical science. The problems of this interdisciplinary field are some of the most fascinating at the interface of chemistry, biology and medicine. The unique format of the ETADS-2022 will allow for in-depth discussions and opportunities to establish new cross-cutting collaborations.

On behalf of our committee, we look forward to welcoming you at the Discussion.

With best regards.,

Convener

Prof. V.S. Vasantha

CH Instruments is a brand of potentiostats used to perform electrochemical analysis and collect electrochemical data. In this video we show how to upload the native files from the PalmSens software and import the file into Djuli.

Djuli is a Cloud database for the storage, analysis and sharing of data, including electrochemical data.

Zimmer and Peacock and ZP AgTech has the entire technology stack to go from the measurement of nitrate molecules in the soil to nitrate data in the Cloud.

The nitrate soil measuring system connects to ZP's Cloud Science Engine Djuli, where third party developers can call upon the data via an API call.

PalmSens is a brand of potentiostats used to perform electrochemical analysis and collect electrochemical data. In this video we show how to upload the native files from the PalmSens software and import the file into Djuli.

Djuli is a Cloud database for the storage, analysis and sharing of data, including electrochemical data.

Metrohm  Autolab is a brand of potentiostats used to perform electrochemical analysis and collect electrochemical data. In this video we show how to upload an excel export from the Autolab software and import the data into Djuli.

Djuli is a Cloud database for the storage, analysis and sharing of data, including electrochemical data.

Biosensors measure biological or chemical reactions by generating signals proportional to the concentration of an analyte in the reaction. Nowadays, they are a crucial aspect of biomedical diagnosis, as well as in other areas of point-of-care monitoring of treatments and progression of disease.

At Zimmer and Peacock, our applications of biosensors include point of care medical and veterinary diagnostics, as well as wearable biosensors. We have also reached the industries of food, agriculture and aquaculture with our biosensing technology. We know that it is not enough to produce just an electrode, we specialise also in functionalizing the electrodes to turn them into sensors; we specialise in adding enzymes, ionophores, antibodies, antigens, RNA, DNA etc to the surface of electrodes to give them specificity.

The first biosensor was developed by Leland Clark Jr in 1956 for oxygen detection, he became known as the ‘father of biosensors’. It wasn’t until 1975 that the first commercial biosensor was developed by Yellow Spring Instruments. Ever since the development of the handheld blood biosensor by i-STAT sensor in 1992 there has been remarkable progress within the biosensor field. The biosensor field has become a multidisciplinary area of research, combining the principles of basic sciences with the fundamentals of nanotechnology, as well as electronics and applicatory medicine. 

One of the challenging problems in wearable and transdermal biosensing development is mimicking the ex-vivo/on-skin/transdermal situation in the lab setting.

In the adjacent image is one of ZP's closest attempts so far, where we have synthesised an artificial skin, but past which we are very slowly flowing a glucose solution. The glucose solution is exchanging with the solutions in the artificial skin.

The test was done over 7 days. If we focus on the green trace (channel 1 with sensor 1) then we see that we have a stable baseline at 0 mM for day 1 and when the flowing solution is changed from 0 mM to 3 mM at the start of day 1 the signal shows a slow increase. The second sensor in the experiment, the orange trace, (channel 2 with sensor 2) is showing a different response as that sensor is at the edge of artificial skin, and is closer to the glucose source.

The timelines associated with the signal changing in response to the glucose changes is governed by the volume of artificial skin relative to the pump rate, i.e. the faster the pump rate relative to artificial skin volume then faster the transients.

Zimmer and Peacock is the World leading ISO13485 contract developer and manufacturer of electrochemical biosensors, including biosensors in marine animals.

When it comes to data transfer from biosensors through seawater to the Cloud there is a range of new problems relative to air, as conductive solutions, such as seawater, interferes with WIFI/Bluetooth/electromagnetic transmission, and so ZP has to adopt creative solutions.

if you are interested in marine biosensing solutions please don't hesitate to contact ZP.

Currently, there has been an increase in the adoption of wearable biosensors as they are useful in several applications such as the continuous monitoring of vitals to combat diseases such as diabetes and cancer. By producing reliable real-time data through non-invasive measures including sweat and saliva, wearable electrochemical biosensors have been of high interest in recent years and have had major developments. By using these non-invasive measures, there is a significant reduction in potential risks to the consumer since they do not contact blood and are much more appealing. Zimmer and Peacock specializes in manufacturing, testing, and developing these sensors to be used in a wide range of applications based on client, patient, and market needs. To increase their comfortability, the sensors are designed to have appealing qualities such as flexibility, conformability, reliability, and convenience, with the patients’ needs being the focal point of every step of the process.

As the usage of wearable biosensors replaces labor-intensive, time-consuming, and expensive lab tests, it is no surprise that there has been an increase in their demand in recent years. Additionally, by using these wearable sensors, it is highly possible for medicine to be personalized based on the patient’s medical requirements. As a result of this, advancements in technology are necessary to continue to provide point of care applications to patients. This has been implemented and made possible through the usage of wearable biosensors which provide continuous monitoring of vital signs to be analyzed at all times. Specifically, these are necessary, but not limited to, children, psychiatric patients, premature infants, as well as athletes. By providing a means to reduce the burden placed on the healthcare industry as a result of a growing world population as well as the strain put on hospitals due to COVID-19, wearable sensors are nothing but advantageous. 

They ease the burden on healthcare professionals and allow space for hospital beds to be used for more urgent cases since they allow remote monitoring and recording of patients’ vitals and signals. It is important to note that professionals expect the world population to increase by 20% over the next 20 years, and so, it is necessary for high-quality health care services to be available. Due to present advancements and recent technologies, this can be made possible. Using Zimmer and Peacock’s technology and expertise in this field, we are able to deliver these sensors with the highest quality to meet consumer’s demands.

ZP is the world's leading ISO13485 contract developer and manufacturer of electrodes for electrochemical biosensors and IVDs. In this video we discuss the technology from Macias Sensors for using PCB gold as an electrode in sensing applications.

To test the gold in your application please click the button below.

The ZP Team has been busy this week designing 3D printed accessories to  support our screen printed electrode range. 

Contact ZP to get  hold of the STL files so you can print these accessories.

These files will be made freely available to our screen printed electrode customers.

At ZP we are very much focused on electrochemical biosensor/IVD development and manufacturing. ZP has a very broad engineering skill set which includes fabricating auxiliary silicone  parts  as discussed in this video.

These microneedles patches from ZP are available as a blank polymer or metallized with platinum or gold.

In addition for those interested in cosmetics or  drug delivery etc please contact ZP regarding the formulation and immobilization of drugs and materials onto these patches for  transdermal drug applications.

The videos on this page are intended to give an introduction to these microneedles patches.

At ZP we have built Djuli to be inline with Clinical and Laboratory Standards Institute standards: EP06-A, EP05-A3, EP07, EP12-A2. EP-A3. EP17-A2, EP19, EP25-A...

EP06-A focuses on determining the linearity of a diagnostic, whilst EP05-A3 can be used to determine precision, including manufacturing precision/repeatability/reproducibility.  In this video we show how Djuli can be used to determine linearity inline with EP06-A, and how data can be compared within Djuli in order to address EP05-A3.

As part of ZP's ISO13485 contract manufacturing of invitro diagnostics we use Djuli to batch release IVDs as part of our out-going-quality-control (OQC), and so have validated Djuli's stats algorithms.

Welcome to the Djuli database.

Please click the image adjacent to register and login.

Zimmer and Peacock is the World's fastest growing ISO13485 contract developer and manufacturer of electrochemical biosensors, wearables and IVDs.

As part of our growth strategy ZP is making smart, strategic investments in businesses that are aligned with our strategy and growth.

So far the ZP Group has:

1) Invested in our longest running clients.

2) Helped over five entrepreneurs launch their dream companies.

3) Bought the assets and taken on the staff from struggling companies in our space

4) Licensed multiple technologies from the University Oxford UK.

5) Formed multiple Joint Ventures with a range of clients as part of their go-to-market strategy

The features of a deal that help with the fit between you and ZP are:

1) ZP must be able to add value to your business other than just cash flow, this value could be: our development, our manufacturing, our technology stack, our sales and marketing reach ,new markets for our core competencies.

2) ZP is looking to be part of the supply chain, so your success can be part of our success.

3) ZP will assign Directors to your board to help guide the growth of your business.

4) ZP is able to  invest through: people, technology and financial. When ZP makes a financial investment the entrepreneur has be be able to demonstrate a source of additional funding from: other investors, grants etc.

One of the empowering benefits of a ZP investment/involvement is the possibility of carry the endorsement/licence 'Powered by Zimmer and Peacock'. 

This has enabled businesses to punch above their weight as it demonstrates an approval and/or an involvement from the ZP Group. 

In 2022 ZP is sponsoring a PhD with the University of Birmingham.

In 2022 ZP is recruiting interns from the University of Birmingham Chemistry Department.

In 2022 ZP is recruiting interns from Imperial College.

A detailed article on unlocking your Experimental Network Value

A detailed article on unlocking your Experimental Network Value

A newsletter from ZP for January 2022 on biosensors, sensor and IVDs.  In this newsletter we curate the articles and news from ZP that has the highest benefit for our readers.

The big issue during any R and D effort is unlocking the full value from your experimental resources.

The Experimental Network Value (ENV) is a measure of how powered your R and D efforts are, and is a function of the number of experimentalists/scientists/engineers you have within your entire network and the degree of connectivity between them.

A large group of experimentalists that are employed but are poorly connected will have a low ENV value, whilst the same team when highly connected will have a high ENV.

Djuli is designed to ensure the highest ENV for your R and D efforts.

Djuli is a Cloud database from ZP designed to maximise the Experimental Network Value (ENV) of your experimental effort and make your experimental programme strong , rather than a source of frustration. Djuli does this by:

• Enforcing an experimental structure into your programmes.
• Ensuring that experimental results are reported in a consistent manner.
• Allowing the experimental reports to be easily searchable.
• Allowing real time visualization of experimental progress.
• Centralizing the storage of your experimental efforts.
• Ensuring the custodianship of your experimental data.
• Allowing experimental team that are geographical dispersed to work in the same place online.
• Sharing experimental data with internal and external stakeholders, through permissions settings.
• Allowing collaborating experimentalists to contribute directly into your programmes, including uploading into djuli.
• Avoiding the loss of experimental data within unstructured folder systems.
• A scalable system as  djuli allows a new user to effortlessly set up an account, and then the Cluster owner can invite them to view, edit and contribute to the experimental effort.

Welcome to the Djuli database.

Please click the image adjacent to register and login.

The Experimental Network Value (ENV) is the value of your experimentalist network based on the number of experimentalists within your internal and external networks and is calculated based on the assumption that your scientists/engineers/experimentalists can see each other's  experiments through a Cloud sharing system such as Djuli. 

EXPERIMENTAL NETWORK VALUE OF ZERO

EXPERIMENTAL NETWORK VALUE OF FIFTEEN

A common issue in many organizations is that individual experimentalists could be saving their data in different repositories or silos, or in the worst case on local computer drives, which are not backed up.

Though generic Cloud storage (One Drive, Google drive and Dropbox) seem like a solution these are not optimized for experimental lab data, and lab data can end up being distributed across files, folders and locked within personal folders.

Djuli ensures a centralized repository for your experimental data and effort, leaving it in a standardised, searchable and sharable format.

Djuli has a structure consisting of Cluster, Projects and Reports. 

At the top level of the Djuli structure are Clusters, these are set up by the Senor Experimental Manager, and imposes the organization structure in which the experimentalists will build the content through their experimental efforts.

Under the Clusters are Projects. For example In the case of ZP we may have a Cluster called Fishtag and within the Cluster we have two Projects called Glucose and Cortisol. Under Projects in the Djuli architecture are Reports, this is where the experimentalist places details, data and information generated during an experiment. In the case of glucose sensor data this will go into the Glucose project as reports, whilst cortisol sensor data goes into the Cortisol Project as Cortisol Reports.

An important feature of Djuli is that it ensures that experimental data is saved in one location and is searchable.

It is not uncommon that two years into a large programme that experiments can start to be repeated and so it is very important to  know where the data is and to be able to search the historical record, both to remember and learn from the past and not to duplicate past efforts.

Djuli is built on the tenet that experimental collaborations within teams and between teams are more powerful than experimentalists working alone or teams that are not efficiently connected.

A key feature of Djuli is the ability to increase the ENV of any experimental effort by using the permissions based  sharing of data. By sharing data through Djuli  with internal and external collaborators then the ENV of the programme increases.

ZP is now recruiting for University of Birmingham Chemistry Students for  3-month and 12-month placements at our facilities in the UK and Norway starting 2022.

To see internship updates from ZP follow us on social media.

ZP is now recruiting for Imperial students for  3-month and 12-month placements at our facilities in the UK and Norway starting 2022.

We have historically recruited from the STEM subjects, but we welcome applicants from all disciplines.

To see internship updates from ZP follow us on social media.

A PhD is now available with the University of Birmingham sponsored and co-supervised by ZP.

Project title: Screen-printed Nanobody Switchable Sensors for Cell Therapy process Monitoring

Professor Paula Mendes from the University of Birmingham talks about her lifETIME CDT 2022 #PhD project working with Zimmer and Peacock.

Cell and gene therapies are poised to transform medicine by providing personalized and effective treatments for patients with chronic or life-threatening diseases. However, the complexity and high costs linked with the manufacturing of cell and gene therapy products have been severely constraining market availability and patient accessibility to these life changing therapies. There is an urgent need for innovative technologies that can address current challenges facing cell and gene therapy manufacturing. Major advances are needed in process integrated analytical tools to accurately and reliably measuring in real-time key attributes of cells throughout the manufacturing process. This interdisciplinary project aims to develop disposable, low-cost electrochemical sensor technology for real-time monitoring of cell secreted protein biomarkers. We are combining for the first time the capability to control binding on-demand using switchable receptors with screen-printing technology. Conceptually different from established biosensors where the surface immobilised affinity binding receptors act as passive probes, we introduce sensor devices, which enable active manipulation of single-domain antibodies, i.e. nanobodies. Consequently, analytes can be capture in space and time for detection, allowing the sensor devices to support real-time data capture for different periods of time. It will provide an exceptional opportunity to implement fully automated, robust cell therapy culture processes and bring down production costs, ultimately delivering cost-effective and impactful therapeutics to patients in need.

TITLE - Workshop on electrochemical bio-sensing by Zimmer and Peacock

ABSTRACT - Zimmer and Peacock will be presenting a workshop on bio-sensing technology at the 7h International Conference on Bio-Sensing Technology. The workshop will cover voltammetric biosensors, amperometric biosensors, potentiometric biosensors and impedance biosensors. There will be three elements to the workshop:

1) Introduction to voltammetric biosensors, amperometric biosensors, potentiometric biosensors and impedance biosensors. 

2) Real world examples as to how the techniques can be or are currently utilized in biosensing.

3) Live and interactive demos of the techniques using potentiostats and screen printed electrodes and biosensing.

The workshop will draw upon the industrial experience of ZP and so will strongly focus on practical biosensing rather than theoretical biosensing.

TIME AND DATE - 22 May 2022 in the afternoon.

VENUE - Meliá Sitges Hotel Congress Centre, Sitges, Spain.

Zimmer and Peacock has the World's broadest range of electrochemical biosensors, to accompany this ZP also has a seasoned electromechanical team who provide OEM electronic solutions to our clients and customers.

The journey for any specific biosensor, in-vitro diagnostic or wearable biosensor is very individual, and is based on both technical and non-technical considerations, including: the target analyte, the form factor of the product, the target market, whether the correct funding is in place, and whether it is a regulated or unregulated application/market, etc. 

On this page we discuss the technologies and workflows that Zimmer and Peacock has in place to accelerate the productization and  commercialization of electrochemical biosensors, IVDs and wearable electrochemical biosensors.

You will note that in the ZP contract ISO13485 biosensor and IVD development and manufacture we don't focus on a single aspect of the sensing system , this is because we understand that all aspect of the sensing system have to work together and so we avoid the confusion of multiple vendors supplying a single aspect to the product development and confusing as to who is ultimately responsible for the system performance.

At ZP we understand the interaction between the electrode, the assay, the electronics, the fluidics and the quality system, and so the real value add from ZP is when we can work with your internal team to ensure that all aspects are tuned to work together.

In ZP's workflow the first questions are;

1) What is it you are trying to measure?

2) Does ZP have the sensor already, do you have a sensor, or does the sensor need to be developed?

Even if the sensors exists then  they may have to be tested in a matrix that is more relevant to the final application, these include: saliva, breath, nasal swab, blood, sweat, tear film, interstitial fluid etc. 

A good first step with ZP is a proof of principle study.

Zimmer and Peacock would aim to deliver to a Technology Readiness Level (TRL) 3 to 4, and Manufacturing Readiness Level (MRL) 4 to 5, but these are highly dependent on the specifics of the programme - read more.

In STEP ONE we will have proven that the technology idea works in principle; in STEP TWO we are planning the programme and agreeing the Frame-Work-Agreement that will govern the relationship between ZP and the client.

The deliverables are at least a Gantt Chart, a presentation and if both parties agree a signed Frame-Work- Agreement.

It should be noted that the correct planning phase effort should take at least 50 to 100 hours. The timelines of the final plan are in part controlled by the total client budget and the rate of funding available. In order to plan then the ZP team will of course need input from the client.

The philosophy at ZP is to move technology out of the lab as soon as possible (ASAP). The ease of doing this is dependent on what ZP discovers and develops in STEP ONE,  but important factors include: Limit-of-Detection (LoD), immunosensors versus enzyme sensors, IVDS versus wearable.  The planning in STEP TWO is similarly important for this STEP THREE, as ZP will use outputs from STEP ONE and STEP TWO to calculate details like the effort to fabricate the sensors required in this STEP THREE.

The intention of STEP THREE (The ZP Accelerator) is to find out issue in the real world with real samples. 

Zimmer and Peacock is an ISO13485 contract developer and manufacturer of electrochemical biosensors and IVDs, which is relevant when discussing MVP.

In the software industry MVP is clearly a product with the minimum feature set that allows users/customer to start using the product. The concept of MVP can be applied into the biosensor and IVD applications, but extra consideration has to be put into the quality management system (QMS)  around the product. The timelines and cost of the MVP are really dependent again on the technology, markets, regulatory landscape and most importantly the ability of the ZP collaborator to fund their product development programme.

The concept of MVP and iterative product improvement is distorted in the medical field, as changes in a medical product are very carefully controlled and changes can cause the need for the product to be re-submitted to regulatory bodies for expensive re-examination.

The first three steps are really just the start of the effort, once we have achieved STEP ONE, TWO, THREE and FOUR then the technology development for the first release of the product is mostly done, but now we are left with ensuring supply of high quality products for clinical studies so that there is sufficient data for supporting submissions to regulatory authorities, whether it is FDA, CE marking, 510(k) etc.

Zimmer and Peacock would aim to deliver to a Technology Readiness Level (TRL) 9 and Manufacturing Readiness Level (MRL) 7 to 9 but these are highly dependent on the specifics of the programme and most importantly the funding in place- read more.

ZP is an ISO13485 contract developer and manufacturer of electrochemical biosensors and IVDs. As one completes regulatory submission or receives CE marking etc., and maybe enters into the second or third year of sales then it may be necessary to then ramp up to full scale manufacturing. At the time of writing this article ZP's largest facility is 4000 square meters and so is able to host most scales of manufacturing.

The intention here is MRL10 -  read more.

The BakeSense Application is an application of the Djuli database.

The Djuli database is a cloud database technology for the uploading, storing, sharing, analysing and categorizing of data, from a range of data sources including: electrochemical data to photos,  images, etc.

On this page we discuss the use the BakeSense Application for Djuli.

For the BakeSense Application your data and images are stored on the Djuli database, so you will first need a Djuli Account. Please click the Djuli button to go to your account or register for an account.

Contact ZP for the app.

Once you have completed Step One and Step Two. You can start to take pictures of the biscuits/cookies. When you take pictures you will be prompted to rank the cookies/biscuits as overcooked, uncooked or cooked. You are essentially training the Djuli database to understand what you consider well backed cookies, over baked cookies and under backed cookies.

An image can be used to train the database by clicking over-cooked, under cooked or cooked.

You can see your data on our Cloud database login into the Djuli database using the button here. The database is best viewed from a larger screen such as a PC, Chrome notebook or Mac etc.

Though many teams talk of using low cost PCB (printed circuit board) fabrication to make gold electrodes for electrochemical sensors and biosensors, the truth is that PCB gold is too imperfect a surface to be used in applications where aqueous samples are in contact with the electrodes.

This problem has been fixed by Macias sensors, who have developed a PCB fabrication technology for gold electrodes where the electrodes act as pristine gold.

In the adjacent image a solution of ferricyanide was tested  using standard PCB fabricated electrodes and Macias Sensors fabricated gold PCBs. It is clear to the electrochemistry community that the Macias Sensors showed a classic behaviour in the ferricyanide solution, where as the standard PCB gold shows just anomalies that are a reflection of the unsuitability of the standard PCB gold to electrochemical sensor and biosensor applications.

The array of nano-holes/nano-pores in these silicon devices offer interesting applications including as nano-sieves.

Contact ZP to discuss customization.

Zimmer and Peacock offers Cloud Solutions around the storage, sharing and analysis of data.

One application for our technology is image recognition, including determining whether products have the correct colour or appearance.

In the video we analyse Jaffa cakes and Digestives, though the technology is generic and can be trained for other products, including non-food applications.

Zimmer and Peacock has the World's widest range of electrochemical biosensors.

What makes biosensors different from other types of condition sensors such as movement, accelerometers, GPS, pressure and temperature is that the biosensor is in intimate contact with the sample; in other words the sensing material is in direct contact with the sample be it: urine, blood, saliva, sweat, cell culture media, beer, wine, soil etc.

In these types of applications where the sample matrix is complex then the biosensors from ZP can't be viewed as  a single discrete component, but rather as one part in an entire stack of technologies including: the sensor, the electronics, the sensor reading methodology, the data extraction methodology etc.

In applications where spot testing, discrete measurements or especially in extended time continuous measurements then ZP's Biosensor to API Service maybe  more appropriate, as this allows ZP to bring the data to the ZP Cloud where ZP's algorithms  can condition the signal to information and then bring the information to the clients' solutions via an application programme interface (API).

This biosensor API product and service offering from ZP leverages, ZP's sensors, electronics and Cloud.

During this COVID-19 pandemic the FDA's policy on emergency authorization (EUA) has been a very useful lever in catalysing innovation and investment for accelerating diagnostic tests to the market, but the medical diagnostics industry has now been warned in a recent FDA EUA policy revision that the requirements for the granting of a diagnostic under EUA just became stricter. 

Though the policy revision is fairly short at twenty pages for those who want  a summary then please consider the following points:

• POINT ONE - If your diagnostic is a point of care device (PoC) and/or can be used at home then the FDA will consider you for EUA, but consider POINT TWO.
• POINT TWO - You must be able to provide convincing evidence that you can manufacture at volumes in excels of 500 k tests per week, within 3-months of the EUA granted.
• POINT THREE  -EUA requests for tests which come from or are supported by a US government agency  such as Biomedical Advanced Research and Development Authority (BARDA) or the National Institutes of Health’s Rapid Acceleration of Diagnostics (RADx) will be prioritized.
• POINT FOUR - For tests not authorized and not being offered at the time of the publishing of the revised EUA policy, approximately 15 November 2022, then the FDA may only review EUA requests from priority tests, see POINTS ONE, TWO and THREE above.
• POINT FIVE - If the FDA does not receive a confirmation from a test developer that submitted its EUA request prior to February 1 2021 confirming that the developer wants the FDA to continue reviewing its EUA request, then the FDA intends to decline to review, or may decline to further review if the review has already begun.

ABOUT ZP

Zimmer and Peacock is the world's leading ISO13485 contract developer and manufacturer of electrochemical biosensors and IVDs. Our services include CE marking and FDA submissions for the devices we develop and manufacture with our partners.

In the same week that ZP launches a series of screen printed pH sensors and a screen printed graphene electrode we are also authors on a new paper featuring screen printed graphene pH sensors.

At ZP we are repeatably asked how long electrochemical CGM sensors can last for. At the ZP facility we have CGM sensors that have been continuously running for over 125 days.

Zimmer and Peacock is the only contract ISO13485 electrochemical biosensor and IVD developers able to deliver minimum viable product in 6 months.  This is because the ZP team has been together for several years and so the workflows necessary to rapidly develop MVP biosensors and IVDs are intrinsic in our DNA.

ZP will be attending stakeholder day at the University of Glasgow on the 18 January 2022.

The stakeholder day will bring together lifETIME students, academics, industry partners, iClub members and steering group. The purpose of the event is to capture our stakeholder views form which the management will use to refine the CDTs impact strategy.

Zimmer and Peacock have manufactured the World's most commercially applicable graphene electrodes.

These graphene electrodes are selling for 390 Euros for a pack of 200 electrodes;, so for R and D purposes these graphene electrodes retail individually at 1.95 Euros each.

Contact ZP to have pricing for larger scale volume.

The SARS-CoV-2 CoronaCheck from Exhalation using ZP/Aliksir virus detection sensors was deliberately designed and patented to be future proofed for future SARS-CoV-2 variants, including Omicron.

A key part of this patented sensing technology is that it targets the surface of the virus, specifically  those elements of the virus surface which give the virus its transmissibility  and lethality. 

As SARS-CoV-2 variants, such as Omicron, have emerged their increased rate of  transmittance  means that it is easier for CoronaCheck System to detect the SARS-CoV-2 virus within the patient sample.

The ZP Sensing/Aliksir technology at the heart of CoronaCheck is unlike other SARS-CoV-2 detection technologies and has many advantages over other technologies as discussed below.

Lateral flow strips - Lateral flow strip for COVID-19 detection is a post infection test for COVID-19, and so does not work if someone is newly infected and/or has not shown a 'significant' immune response.

RT-PCR - Though RT-PCR is held as the gold standard for COVID-19 diagnosis it is not necessarily a 'good' technology for rapid testing in a point of care format (PoC). This is because the workflow for RT-PCR is multi-stepped, including: lysis, purification, reverse transcription, polymerase chain reaction, amplification, and detection.

The ZP Molecular In-vitro Diagnostics Group are experts in developing molecular biology assays.

Symptomatic Sensors - A viral infection can be associated with raised patient temperature, coughing and with some viruses sneezing. Though it seems elegant to diagnose COVID-19 from temperature and coughing these are not accurate due to the false positive and false negative rates. Regarding temperature and coughing these symptoms are associated with a plethora of diseases including asthma and influenza infections, so relying on them to diagnose COVID-19 can lead to high rates of false positives.  With regard to COVID-19 among the young it is possible to have SARS-CoV-2 but for the patient to be  asymptomatic and so relying on symptoms with an asymptomatic patient can lead to a false negative result. 

ZP had a great opening to it's new office on the Swansea University Campus.

As part of our long term commitment to Swansea University ZP has established the ZP Swansea Office.

ZP was delighted to sponsor  the team from the University of Rochester who won gold at iGEM2021, the team used the ZP Hyper Value Carbon Screen Printed Electrodes (SPE) to developed a sepsis sensor.

Thank you so much for being a sponsor of our iGEM team, we are very grateful for your help in the development of our sepsis diagnostic device. As the 2021 iGEM competition has now come to a close, I wanted to update you on our results. Our team won a gold medal at the competition and received nominations for Best Diagnostic Project, Best Education, and Best Hardware. With these three nominations and our gold, we are happy to be the second-most-awarded iGEM team in North America! We could not have done this without your help, and we thank you so much for your generosity.

Zimmer and Peacock are delighted to be exhibiting at the 2022 Bioelectrochemical Society -

BES 2022 XXVII International symposium on Bioelectrochemistry and Bioenergetics.

ZP is the world's largest supplier of quality R and D screen printed electrodes and so we are delighted be co-exhibiting with PalmSens at the symposium.

These are dual potentiostat that are used in conjunction with ZP micro-biosensors.

The output of these potentiostats are sent to a third-part data-logger.

Zimmer and Peacock is an invited speaker at LOPEC 2022

Conference: March 22–24, 2022 | ICM – International Congress Center München

ABSTRACT

At ZP we see that electrochemical biosensors are a critical part of several Social and Commercial Revolutions, including the Internet of Things (IoT), Sensor Web, growth of the In-vitro Diagnostics Market (IVD), rapid testing in the Food and Beverage Industry and wearable biosensors for Medical and Wellness Tracking.

In this talk ZP will introduce the entire technology stack going from a biological sample to actional information delivered by Cloud Analytics. At ZP we have a special interest in the front end of the technology stack, the electrochemical biosensor, which is a combination of: printing, electronics, materials science, chemistry, and biology. Therefore, a special focus of the talk will be on the science of biological/biochemical sensing using printed electronics.

Thank you for talking to ZP at Medica.

In the adjacent video we summarise the topics covered at Medica, and we have buttons linking to supporting information below.

Come and see ZP at D21 in Hall 12 at Medica today.

In the adjacent video ZP highlights some core technologies and capabilities.

Zimmer and Peacock manufactures the World's most repeatable screen printed gold electrode. 

The ZP difference with the ZP gold screen printed electrodes is that we  electrochemically test the batch of screen printed gold electrodes before we release them to the market.

ZP takes particular care of our gold screen printed electrodes because we use them in our own projects and products, and so we are 100 % aligned with our clients in needing the best screen printed electrodes.

Please scan the QR code or click the button to have ZP contact you after Medica.

ZP and PalmSens held a very successful webinar on the use of PalmSens technology and ZP nitrate sensors, you can re-watch the webinar here.

At ZP we do have certified project managers and we use Gantt Charts and effort tracking to control our programs, in this video we discuss that the development of a biosensor or IVD system is not a sequential effort, but rather we have all the elements running in parallel, this is possible because most IVD development at ZP is not invention but rather a re-purposing of existing ZP technologies and workflow towards  the specific targets of the collaborator.

Zimmer and Peacock has the most stream lined electrochemical development and manufacturing workflows. In the adjacent video we describe our contract biosensor/IVD development workflow for an agile and iterative biosensor development.

This webinar has now completed but see the webinar below.

Zimmer and Peacock will be holding a live webinar with IIT Bombay

TITLE: Nanobios Lab IIT Bombay and ZP - Agriculture Webinar

WHEN: 2:30 PM India 02 November 2021.

ZP will be exhibiting at Medica 2021 in Hall 12 booth D21.

ZP is delighted to be a panellist at Sensors in Medicine 2021.

Panel Discussion Wednesday 10th November 5:00 - 6:00 pm GMT 

Moving sensor technology from lab to marketplace

There are literally hundreds of new sensors technologies reported each year but very few of them make it to market or clinic.   A recurrent theme at previous Sensors in Medicine conferences has been the barriers to commercialising new technology.   At SiM21 we propose to reverse the issue and look at what is required to make a new sensor technology successful.   After opening statements by our guest panel who all have significant experience in commercialising new technology,  the  topic will be open for discussion by everyone.   

The Panel

Steve Whalley,  Moderator,  has 30+ years of experience in the semiconductor,  MEMS,  and sensors industries,  including 25 years with Intel.   He has led complex international development projects. Rouzet Agaiby  is an  Associate Director at eg technology Ltd where she enables clients to articulate their ideas and understand the processes involved in taking these ideas and turning them into real,  marketable products. 

Martin Peacock  is a founding Director at Zimmer and Peacock,  among the fastest growing sensor companies,  focused on partnering to bring collaborators biosensors and medical diagnostics to market,  through development and ultimately manufacturing.

Anne Lane  is CEO at UCLB, the technology transfer business of University College London.   She has extensive experience in commercialising technology in an academic environment.

Rouzet Agaiby  is an  Associate Director at eg technology Ltd where she enables clients to articulate their ideas and understand the processes involved in taking these ideas and turning them into real,  marketable products.

ZP is now recruiting for Swansea students for  3-month and 12-month placements at our facilities in the UK and Norway starting 2022.

We have historically recruited from the STEM subjects, but we welcome applicants from all disciplines.

Sorry registration is now closed, follow us on social media to see future opportunities.

ZP has the world's widest range of micro-biosensors for neuroscience studies.

In the adjacent image the effort to quality control the biosensors is shown.

ZP is the world's leading manufacturer and developer of vapour deposited electrodes and screen printed electrodes. We are also very active developers of sensors upon these electrodes. In this video we demonstrate the electrochemical deposition of Prussian Blue.

The electrodes in the image and video are our value gold electrodes.

In the adjacent image ZP has fabricated a microfluidic channel from microscope slide and cover slip.

ZP fabricates such devices as part of its services to help bring our clients to market.

In this video we discuss the design of electrodes, which can be applied to screen printed electrodes or sputtered electrodes. The opinions given are specifically from a perspective of electrochemical sensing and biosensing.

At ZP we keep very accurate records on the true effort it takes to develop an electrochemical in-vitro diagnostic. We recently reviewed an on-going programme and so far we have averaged 334 hours per month.

ZP is the only IS013485 company that takes a holistic approach to electrochemical biosensor development, and so we don't artificially separate the sensor, hardware, firmware software, manufacturing and quality systems from one another, and this is reflected in our ZP Accelerator platform.

Cyanide is a potential source of poisoning in cattle, the result is a reduction in oxygen throughout the body. This week we discuss cyanide detection using electrochemical biosensing of cyanide.

Zimmer and Peacock along with our partners PBL and JIC have developed the world's first commercially viable soil nitrate sensor, which can be used in the  precision farming of crops such as potatoes and wheat etc.

ZP will be a the Potato Industry Event on the 24 and 25 November 2021 with the nitrate rod so please contact us to meet us there.

Zimmer and Peacock are the world leading ISO13485 contract developer and manufacturer of electrochemical biosensors and screen printed electrodes (SPEs).

We are delighted that our colleagues in Macnica have made a video featuring the ZP Hyper Value Electrodes and their use in the analysis of caffeine in coffee.

The Maillard reaction is an important reaction in the Food Sciences, and is responsible for the production of acrylamide when roasting coffee beans. This acrylamide is both present in fresh roasted coffee and instant coffee and the allowable amounts in coffee are regulated by the EU and the US FDA. In this video we discuss some work by one of ZP Developer Zone members who used the AnaPot and the HVSPE (Hyper Value Screen Printed Electrode) to develop a new method for acrylamide detection in coffee.

This week ZP is having it's Company Meeting. As part of the event we are encouraging everyone to take photos and after the event we will have a company wide vote and the winner will win a 100 Euro Amazon Voucher.

There are unlimited photo entries per person, so snap away.

The theme of the competition is 'The Spirit of ZP'.

The winner will be voted for by the entire company.

Zimmer and Peacock will be holding a live webinar and demonstration with Shiraz University.

TITLE: Modern Electrochemical Biosensing

ABSTRACT: A modern approach to electrochemical biosensing, including a live demonstration of biosensing using Smart Phone Technology. 

WHEN: 4:00 PM Tehran Time 27 October 2021.

SPEAKER: Dr Martin Peacock Director and Honorary Senior Lecturer

One of the founding members of the ZP developers Zone, Hasim, recently gave a talk at the International Symposium on Food and Agriculture on the analysis of acrylamide in coffee and instant coffee.

Zimmer and Peacock will be speaking at the Curam Summit on the 13 October 2021.

We will be talking about: Commercialisation of Smart Medical Devices - a personal perspective

At ZP we love to interact with PalmSens through our joint webinars, as it a partnership between a strong R and D potentiostat manufacturer and a World class ISO13485 contract developer and manufacturer of electrodes and electrochemical biosensors.

In this video we give a practical demonstration on measuring salinity using conductivity, sometimes referred to as an EC measurement. 

WIN: 250 hours and 5000 Euros to work on your idea

WHEN - On the afternoon of Wednesday 06 October 2021 ZP will be hosting a ZP Company Hackathon, where the overall ZP team will receive pitches from individuals or teams from ZP.

IDEA - The thesis is that the ZP team has the best ideas and so as a company we should be willing to invest in the ideas of the team which align with ZP being the best possible biosensor company we can be.

YOUR IDEA - Ideas are not limited to biosensors, your ideas can be around: sales, marketing, logistics, manufacturing, academic engagement, sustainability, biosensors, biosensor applications, microfluidics, new materials, Cloud computing, apps etc etc etc.

Zimmer and Peacock will be hosting a hands on biosensor workshop at the Bio-Sensing Technology Conference.

This event will be in the afternoon of Sunday 22 May 2022 Sitge, starting at approximately 2 PM local time.

Zimmer and Peacock's ZP AgTech will be exhibiting at Farm Business Innovation 2021 at the Birmingham NEC on the 10 and 11 November 2021.

Please come and see us there.

Zimmer and Peacock has the largest range of CGM (continuous glucose monitoring) technology on the market, as part of this application support we produce webinars and support material around the technology. 

In the video excerpt we discuss the recent renaissance in reverse iontophoresis.

Zimmer and Peacock has the largest range of CGM (continuous glucose monitoring) technology on the market, as part of this application support we produce webinars and support material around the technology. 

In the video excerpt we discuss non-invasive CGM. 

Zimmer and Peacock are the world's largest ISO13485 contract developer and manufacturer of electrochemical biosensors, IVDs, wearable biosensors, screen printed electrodes, MEMS, BioMEMS and vapor deposited electrodes.

We make sensors, screen printed electrodes, electronics etc available on our website as a service to academics, entrepreneurs, scientists, and engineers in order that you can rapidly develop ideas, try out concepts or investigate applications and testing challenging samples.

The products on our website are intended for R&D purposes only, and their use in human and animal application is only with ZP's express permission. 

The products on ZP’s website are intended to allow the developer to answer questions like lifetime, sensitivity, limit of detection, signal stability etc. for the specific applications that are being developed.  We expect that each developer has a very specific sample be it: soil, water, blood, urine, serum, plasma, air, oil, fat, saliva etc. As each sample is different the specifications developed for one application or sample may not necessarily apply to another. There is descriptive data and videos posted on the specific biosensor webpage as a guide.

The webstore offers a convenient way to BUY and TRY, for example a set of electronics for a glucose application can be purchased for less than 300 Euros and two R and D glucose sensors for less than 100 Euros. This means that for many applications the products on the ZP website can provide quick answers to applications in days and weeks as opposed to months and year, which was the case before there was a ZP.

ZP has fully functioning R and D laboratories alongside our manufacturing facilities and so from these R and D Centres we are able to offer advice to clients though our consulting services or we can provide practical R and D services to develop new tech or to explore  new applications.

ZP hired two NTNU students in 2021, and we have places for many many more. We will be coming to NTNU Kjemidagen on the 19 October 2021, if you are interested in helping to shape the ZP story please come and see us.

PROCEDURE

1. Connect the SPE ZP pH sensor to the connector on GFET 

2. Connect the GFET using a micro USB cable to the PC

3. To verify if the device is connected properly and enumerated as a COM port, open Control Panel->Device Manager->Port and find COM number (COM5 in this case).

4. Open any terminal application such as TeraTerm (https://osdn.net/projects/ttssh2/releases/) to view the data from the GFET. The baud rate must be set 57600 bps.

5. Once the device is connected the user can see the oxygen measurement values in volts displayed in the user interface (see image). The data can be later used in Microsoft Excel or python script for further processing and visualization.

Zimmer and Peacock are often asked to recommend a screen printed electrode or electrodes for molecular imprinted polymers (MIPS). In the adjacent video we discuss a paper from members of the ZP Developer Zone on how to construct a MIPS devices on top of a ZP screen printed electrode.

Zimmer and Peacock has a suite of granted patents for the manufacture and clinical application of purine sensors for improving the diagnostics and subsequent treatment for human health applications.

Zimmer and Peacock are a founding partner at the Centre for Integrative Semiconductor Materials (CISM).

Our partnership with CISM is in line with our UK expansion, which includes new facilities in Swansea, and is in line with ZP being the world's largest ISO13485  contract BioMEMS developer and manufacturer.

The ZP difference in BioMEMs is that we are able to make the micro/nano featured substrates and to functionalise them with biologically active materials. be it: enzymes, proteins, RNA, DNA, antibodies, receptors, etc.

Zimmer and Peacock is a World leading ISO13485 contract developer and manufacturer of screen printed electrodes and vapour deposited electrodes.

ZP has combined these two manufacturing techniques to produce electrodes configurations where the working electrodes are fabricated by sputtering techniques, whilst the counter and reference electrode is made by screen printing electrodes.

For those wishing to rent the purine sensor see adjacent offers.

What does being a ZP On-campus Ambassador mean?

As a ZP On-Campus Ambassador you are responsible for representing ZP on campus and helping faculty and students engage with ZP, including:

★ Use your  creativity to make exciting social media content & videos

★ Promote ZP's  incredible roles

★ Engage students with ZP

★ Building relationships with societies & faculty members

★ Encourage your peers to do their projects with ZP

★ Encourage your peers to intern with ZP

★ Think creatively and act to promote ZP around campus

What do you get?

★ ZP will pay you for your efforts

★ You will build relationships within ZP which can be invaluable in your future carer, internships and placements

★ You will gain invaluable industrial experience that will look great on your CV/resume

★ Grow in confidence

Zimmer and Peacock are the World's most capable contract ISO13485 contract developer and manufacturer of biosensor technologies including micro/nano holes,  micro/nano pores and arrays.

ZP has the Word's largest commercial BioMEMS group which is fully integrated with our Biosensor Group.

Zimmer and Peacock has built a parallel connector to allow CH Instruments and any other potentiostat where the connectors are crocodile/alligator clips to more easily connect to the ZP electrodes.

This page contains  information useful to attendees of our webinar on the detection of caffeine using the Sensit Smart.

On this page you will find buttons and information relevant to the webinar:

If you missed the webinar here it is again.

Zimmer and Peacock has a lot of training material relevant to the Sensit Smart on our website, please click the adjacent button.

Keep up to do date with technology by following ZP on Social Media

Sign up to the ZP Technology Newsletter.

Free questions to Zimmer and Peacock

Zimmer and Peacock – Biosensor and Medical Diagnostic Placement Opportunities in the UK and Norway.

Zimmer and Peacock is a world leading biosensor development and manufacturing team located primarily in the UK and Norway, so we have placement opportunities across multiple sites for the right candidates.

Our biosensors are used across a variety of applications from medical devices, precision farming, wearable biosensors and the Internet of Things, making this the perfect opportunity for someone who cares about making a difference to peoples’ livelihoods. At Zimmer and Peacock, we are partnering with academia and industry to ensure that there are enough good and commercially available sensors to meet the requirements of these new and growing markets. We innovate around our collaborators’ inventions to help bring ideas to market.

ZP has completed an entire biosensing system from biosensor, to power, to electronics, to data transmission - all in a liquid tight package.

This small package can be tuned to our clients applications.

Zimmer and Peacock offers internships like no others, a 12 month internship with ZP can involve international travel this week the interns arrive in sunny Norway.

Zimmer and Peacock are very greedy and so we have bought ourselves a new robot to join its sisters in our state of the art ISO13485 biosensor manufacturing facility. 

Nitrogen in water

Nutrients, such as nitrogen, phosphorus and potassium, are essential for plant growth and modern agriculture but the overabundance of  nitrogen nutrients in water can cause a number of adverse health and ecological effects. Nitrogen is a plant nutrient when in the forms of nitrate, nitrite, or ammonium, is a nutrient needed for plant growth. 

Nitrate is used in modern agriculture to grow crops, and on many farms the landscape has been greatly modified to maximize farming output/yield. Fields have been leveled and modified to efficiently drain off excess water that may fall as precipitation or from irrigation practices.

The concern is that nutrients added in modern farming enters the water system.

What is the regulatory standard for nitrate?

The United Kingdom and European standard for the concentration of nitrate in drinking water is 50 parts per million (50 mg/l).

Eutrophication – Is the process by which a body of water acquires a high concentration of nutrients, especially phosphates and nitrates. These  promote excessive growth of algae. As the algae die and decompose the levels of organic matter and the decomposing organisms deplete the water of available/dissolved oxygen, causing the death of other organisms, such as fish.

Anoxia – is a lack of dissolve oxygen caused by excessive nutrients in waterways which triggers algae growth. When the plants die and decay, oxygen is stripped from the water, which then turns green or milky white and gives off a strong rotten egg odour.  The lack of oxygen is often deadly for invertebrates, fish and shellfish.

Zimmer and Peacock is the world's largest contract ISO13485 biosensor development and manufacturing team of biosensors and screen printed electrodes.

Zimmer and Peacock develops biosensors in a highly industrialised manner, where the number of sensors fabricated and tested in the development phase are in the tens and hundreds, rather than single sensors.