At ZP we keep very accurate records on the true effort it takes to develop an electrochemical in-vitro diagnostic. We recently reviewed an on-going programme and so far we have averaged 334 hours per month.

ZP is the only IS013485 company that takes a holistic approach to electrochemical biosensor development, and so we don't artificially separate the sensor, hardware, firmware software, manufacturing and quality systems from one another, and this is reflected in our ZP Accelerator platform.

Cyanide is a potential source of poisoning in cattle, the result is a reduction in oxygen throughout the body. This week we discuss cyanide detection using electrochemical biosensing of cyanide.

Zimmer and Peacock along with our partners PBL and JIC have developed the world's first commercially viable soil nitrate sensor, which can be used in the  precision farming of crops such as potatoes and wheat etc.

ZP will be a the Potato Industry Event on the 24 and 25 November 2021 with the nitrate rod so please contact us to meet us there.

Zimmer and Peacock are the world leading ISO13485 contract developer and manufacturer of electrochemical biosensors and screen printed electrodes (SPEs).

We are delighted that our colleagues in Macnica have made a video featuring the ZP Hyper Value Electrodes and their use in the analysis of caffeine in coffee.

The Maillard reaction is an important reaction in the Food Sciences, and is responsible for the production of acrylamide when roasting coffee beans. This acrylamide is both present in fresh roasted coffee and instant coffee and the allowable amounts in coffee are regulated by the EU and the US FDA. In this video we discuss some work by one of ZP Developer Zone members who used the AnaPot and the HVSPE (Hyper Value Screen Printed Electrode) to develop a new method for acrylamide detection in coffee.

This week ZP is having it's Company Meeting. As part of the event we are encouraging everyone to take photos and after the event we will have a company wide vote and the winner will win a 100 Euro Amazon Voucher.

There are unlimited photo entries per person, so snap away.

The theme of the competition is 'The Spirit of ZP'.

The winner will be voted for by the entire company.

Zimmer and Peacock will be holding a live webinar and demonstration with Shiraz University.

TITLE: Modern Electrochemical Biosensing

ABSTRACT: A modern approach to electrochemical biosensing, including a live demonstration of biosensing using Smart Phone Technology. 

WHEN: 4:00 PM Tehran Time 27 October 2021.

SPEAKER: Dr Martin Peacock Director and Honorary Senior Lecturer

One of the founding members of the ZP developers Zone, Hasim, recently gave a talk at the International Symposium on Food and Agriculture on the analysis of acrylamide in coffee and instant coffee.

Zimmer and Peacock will be speaking at the Curam Summit on the 13 October 2021.

We will be talking about: Commercialisation of Smart Medical Devices - a personal perspective

At ZP we love to interact with PalmSens through our joint webinars, as it a partnership between a strong R and D potentiostat manufacturer and a World class ISO13485 contract developer and manufacturer of electrodes and electrochemical biosensors.

In this video we give a practical demonstration on measuring salinity using conductivity, sometimes referred to as an EC measurement. 

WIN: 250 hours and 5000 Euros to work on your idea

WHEN - On the afternoon of Wednesday 06 October 2021 ZP will be hosting a ZP Company Hackathon, where the overall ZP team will receive pitches from individuals or teams from ZP.

IDEA - The thesis is that the ZP team has the best ideas and so as a company we should be willing to invest in the ideas of the team which align with ZP being the best possible biosensor company we can be.

YOUR IDEA - Ideas are not limited to biosensors, your ideas can be around: sales, marketing, logistics, manufacturing, academic engagement, sustainability, biosensors, biosensor applications, microfluidics, new materials, Cloud computing, apps etc etc etc.

Zimmer and Peacock will be hosting a hands on biosensor workshop at the Bio-Sensing Technology Conference.

This event will be in the afternoon of Wednesday 25 May 2022 Sitges.

Zimmer and Peacock's ZP AgTech will be exhibiting at Farm Business Innovation 2021 at the Birmingham NEC on the 10 and 11 November 2021.

Please come and see us there.

Zimmer and Peacock has the largest range of CGM (continuous glucose monitoring) technology on the market, as part of this application support we produce webinars and support material around the technology. 

In the video excerpt we discuss the recent renaissance in reverse iontophoresis.

Zimmer and Peacock has the largest range of CGM (continuous glucose monitoring) technology on the market, as part of this application support we produce webinars and support material around the technology. 

In the video excerpt we discuss non-invasive CGM. 

Zimmer and Peacock are the world's largest ISO13485 contract developer and manufacturer of electrochemical biosensors, IVDs, wearable biosensors, screen printed electrodes, MEMS, BioMEMS and vapor deposited electrodes.

We make sensors, screen printed electrodes, electronics etc available on our website as a service to academics, entrepreneurs, scientists, and engineers in order that you can rapidly develop ideas, try out concepts or investigate applications and testing challenging samples.

The products on our website are intended for R&D purposes only, and their use in human and animal application is only with ZP's express permission. 

The products on ZP’s website are intended to allow the developer to answer questions like lifetime, sensitivity, limit of detection, signal stability etc. for the specific applications that are being developed.  We expect that each developer has a very specific sample be it: soil, water, blood, urine, serum, plasma, air, oil, fat, saliva etc. As each sample is different the specifications developed for one application or sample may not necessarily apply to another. There is descriptive data and videos posted on the specific biosensor webpage as a guide.

The webstore offers a convenient way to BUY and TRY, for example a set of electronics for a glucose application can be purchased for less than 300 Euros and two R and D glucose sensors for less than 100 Euros. This means that for many applications the products on the ZP website can provide quick answers to applications in days and weeks as opposed to months and year, which was the case before there was a ZP.

ZP has fully functioning R and D laboratories alongside our manufacturing facilities and so from these R and D Centres we are able to offer advice to clients though our consulting services or we can provide practical R and D services to develop new tech or to explore  new applications.

ZP hired two NTNU students in 2021, and we have places for many many more. We will be coming to NTNU Kjemidagen on the 19 October 2021, if you are interested in helping to shape the ZP story please come and see us.

PROCEDURE

1. Connect the SPE ZP pH sensor to the connector on GFET 

2. Connect the GFET using a micro USB cable to the PC

3. To verify if the device is connected properly and enumerated as a COM port, open Control Panel->Device Manager->Port and find COM number (COM5 in this case).

4. Open any terminal application such as TeraTerm (https://osdn.net/projects/ttssh2/releases/) to view the data from the GFET. The baud rate must be set 57600 bps.

5. Once the device is connected the user can see the oxygen measurement values in volts displayed in the user interface (see image). The data can be later used in Microsoft Excel or python script for further processing and visualization.

Zimmer and Peacock are often asked to recommend a screen printed electrode or electrodes for molecular imprinted polymers (MIPS). In the adjacent video we discuss a paper from members of the ZP Developer Zone on how to construct a MIPS devices on top of a ZP screen printed electrode.

Zimmer and Peacock has a suite of granted patents for the manufacture and clinical application of purine sensors for improving the diagnostics and subsequent treatment for human health applications.

Zimmer and Peacock are a founding partner at the Centre for Integrative Semiconductor Materials (CISM).

Our partnership with CISM is in line with our UK expansion, which includes new facilities in Swansea, and is in line with ZP being the world's largest ISO13485  contract BioMEMS developer and manufacturer.

The ZP difference in BioMEMs is that we are able to make the micro/nano featured substrates and to functionalise them with biologically active materials. be it: enzymes, proteins, RNA, DNA, antibodies, receptors, etc.

Zimmer and Peacock is a World leading ISO13485 contract developer and manufacturer of screen printed electrodes and vapour deposited electrodes.

ZP has combined these two manufacturing techniques to produce electrodes configurations where the working electrodes are fabricated by sputtering techniques, whilst the counter and reference electrode is made by screen printing electrodes.

For those wishing to rent the purine sensor see adjacent offers.

What does being a ZP On-campus Ambassador mean?

As a ZP On-Campus Ambassador you are responsible for representing ZP on campus and helping faculty and students engage with ZP, including:

★ Use your  creativity to make exciting social media content & videos

★ Promote ZP's  incredible roles

★ Engage students with ZP

★ Building relationships with societies & faculty members

★ Encourage your peers to do their projects with ZP

★ Encourage your peers to intern with ZP

★ Think creatively and act to promote ZP around campus

What do you get?

★ ZP will pay you for your efforts

★ You will build relationships within ZP which can be invaluable in your future carer, internships and placements

★ You will gain invaluable industrial experience that will look great on your CV/resume

★ Grow in confidence

Zimmer and Peacock are the World's most capable contract ISO13485 contract developer and manufacturer of biosensor technologies including micro/nano holes,  micro/nano pores and arrays.

ZP has the Word's largest commercial BioMEMS group which is fully integrated with our Biosensor Group.

Zimmer and Peacock has built a parallel connector to allow CH Instruments and any other potentiostat where the connectors are crocodile/alligator clips to more easily connect to the ZP electrodes.

This page contains  information useful to attendees of our webinar on the detection of caffeine using the Sensit Smart.

On this page you will find buttons and information relevant to the webinar:

If you missed the webinar here it is again.

Zimmer and Peacock has a lot of training material relevant to the Sensit Smart on our website, please click the adjacent button.

Keep up to do date with technology by following ZP on Social Media

Sign up to the ZP Technology Newsletter.

Free questions to Zimmer and Peacock

Zimmer and Peacock – Biosensor and Medical Diagnostic Placement Opportunities in the UK and Norway.

Zimmer and Peacock is a world leading biosensor development and manufacturing team located primarily in the UK and Norway, so we have placement opportunities across multiple sites for the right candidates.

Our biosensors are used across a variety of applications from medical devices, precision farming, wearable biosensors and the Internet of Things, making this the perfect opportunity for someone who cares about making a difference to peoples’ livelihoods. At Zimmer and Peacock, we are partnering with academia and industry to ensure that there are enough good and commercially available sensors to meet the requirements of these new and growing markets. We innovate around our collaborators’ inventions to help bring ideas to market.

ZP has completed an entire biosensing system from biosensor, to power, to electronics, to data transmission - all in a liquid tight package.

This small package can be tuned to our clients applications.

Zimmer and Peacock offers internships like no others, a 12 month internship with ZP can involve international travel this week the interns arrive in sunny Norway.

Zimmer and Peacock are very greedy and so we have bought ourselves a new robot to join its sisters in our state of the art ISO13485 biosensor manufacturing facility. 

Nitrogen in water

Nutrients, such as nitrogen, phosphorus and potassium, are essential for plant growth and modern agriculture but the overabundance of  nitrogen nutrients in water can cause a number of adverse health and ecological effects. Nitrogen is a plant nutrient when in the forms of nitrate, nitrite, or ammonium, is a nutrient needed for plant growth. 

Nitrate is used in modern agriculture to grow crops, and on many farms the landscape has been greatly modified to maximize farming output/yield. Fields have been leveled and modified to efficiently drain off excess water that may fall as precipitation or from irrigation practices.

The concern is that nutrients added in modern farming enters the water system.

What is the regulatory standard for nitrate?

The United Kingdom and European standard for the concentration of nitrate in drinking water is 50 parts per million (50 mg/l).

Eutrophication – Is the process by which a body of water acquires a high concentration of nutrients, especially phosphates and nitrates. These  promote excessive growth of algae. As the algae die and decompose the levels of organic matter and the decomposing organisms deplete the water of available/dissolved oxygen, causing the death of other organisms, such as fish.

Anoxia – is a lack of dissolve oxygen caused by excessive nutrients in waterways which triggers algae growth. When the plants die and decay, oxygen is stripped from the water, which then turns green or milky white and gives off a strong rotten egg odour.  The lack of oxygen is often deadly for invertebrates, fish and shellfish.

Zimmer and Peacock is the world's largest contract ISO13485 biosensor development and manufacturing team of biosensors and screen printed electrodes.

Zimmer and Peacock develops biosensors in a highly industrialised manner, where the number of sensors fabricated and tested in the development phase are in the tens and hundreds, rather than single sensors. 

A quick video on functionalizing screen printed electrodes.

EVENT: Amity University, ZP and USN are hosting a joint webinar for members of the Amity University Community on the 19 August 2021.

ABSTRACT

The use of biosensors in point-of-care (POC) testing devices has attracted considerable attention in the past few years, mainly because of their high specificity, portability, and relatively low cost. Especially during the time of pandemic, research community rapidly moving towards rapid POC detection Coupling these devices with miniaturized electrochemical transducers has shown great potential toward simple, rapid, and cost-effective analysis that can be performed in the field, especially for healthcare, agriculture, environmental monitoring, and food quality control. This webinar will focus on current trends and developments in electrochemical biosensors for POC application. Discussion on most recent advances achieved in POC electrochemical biosensor applications, focusing on new technologies and techniques to improve sensitivity, specificity, stability, and response time.

FOODSENSE - E Coli. BIOSENSOR

The FoodSense from Zimmer and Peacock is a biosensors system licensed from Oxford University, where within  30 minutes the E. Coli population in a sample can be determined.

The biosensor on the FoodSense is very specific to E. Coli, bu when asking broader questions regarding whether a system is or is not clean,  it is necessary to have a biosensor with broader sensitivity to pathogens.

CLEANLINESS/DIRT SENSOR

The FoodSense platform is designed to answer the question 'is a specific bacteria present ?', but when asking the more broader question on whether is a system is clean or  'dirty'  then this question can't be answered by a biosensor with very high specificity.

For example a FoodSene E Coli Sensor can detect E Coli, but it can't be used in a hospital setting to  detect methicillin-resistant Staphylococcus aureus (MRSA). This is because the sensor is working as intended and with its high specificity to E coli it is therefore 'blind' to Staphylococcus aureus.

When asking the question whether a system is clean then a biosensor that is broader in applicability is required, therefore ZP recommends our patent protected purine sensing technology. The purines associated with bacteria includes: hypoxanthine, adenosine, ATP and inosine; their presence in the sample/environment is linked to the sample/system microbial load. The advantage of the purine biosensor is it can detects general bacteria activity regardless of whether it is E Coli, Staphylococcus aureus etc. 

FORM FACTOR AND DEVELOPMENT

ZP is the World's largest independent ISO13485 contract developer and manufacturer of electrochemical biosensors, including disposable sensors and wearable sensors. 

ZP is able to accelerate the development of new sensors, sensor form factors and new sensor applications using our ZP Accelerator platform, please contact us to discuss more.

Zimmer and Peacock are the World's leading manufacturer of biosensors and screen printed electrodes, and so we are delighted to be partnering again with PalmSens and their fully functional potentiostat the SensitSmart in another live streaming webinar  from the ZP labs.

ZP is an experienced ISO13485 manufacturers of microneedles, these microneedles are used by our collaborators in a number of applications including: biosensing, drug delivery, inoculation, etc.

ZP is delighted to be exhibiting at Medica 2021

ZP is delighted to be exhibiting at Sensors in Medicine 2021.

Zimmer and Peacock (ZP) is currently in a position to acquire technology and/or technology businesses. We are particularly interested in IP in terms of granted patents, and businesses with ISO certifications, including ISO13485. Our core business at ZP is the development and manufacture of electrochemical biosensors, and so we are interested in the entire technology stack from the electrodes to the actionable information. Please feel free to contact ZP if you know of such an opportunity.

PROCEDURE

1. Connect the SPE ZP pH sensor to the connector on GFET 

2. Connect the GFET using a micro USB cable to the PC

3. To verify if the device is connected properly and enumerated as a COM port, open Control Panel->Device Manager->Port and find COM number (COM5 in this case).

4. Open any terminal application such as TeraTerm (https://osdn.net/projects/ttssh2/releases/) to view the data from the GFET. The baud rate must be set 57600 bps.

5. Once the device is connected the user can see the pH measurement values in volts displayed in the user interface (see image). The data can be later used in Microsoft Excel or python script for further processing and visualization.

PROCEDURE

1. Connect the SPE ZP pH sensor to the connector on GFET 

2. Connect the GFET using a micro USB cable to the PC

3. To verify if the device is connected properly and enumerated as a COM port, open Control Panel->Device Manager->Port and find COM number (COM5 in this case).

4. Open any terminal application such as TeraTerm (https://osdn.net/projects/ttssh2/releases/) to view the data from the GFET. The baud rate must be set 57600 bps.

5. Once the device is connected the user can see the pH measurement values in volts displayed in the user interface (see image). The data can be later used in Microsoft Excel or python script for further processing and visualization.

Rapid prototyping for biosensor development at ZP is not a single 3D printer in the corner of the mechanical workshop, but rather it is a set of 3D printers with different printing modalities.in their own dedicated room.

To find out how the large, strong and well equipped ISO13485 contract development and manufacturing team can support you please click below.

At ZP we recognise that there are many good biosensors and IVD ideas that do not make it to market. One of the reasons for this lack of progression is that the right commercialisation team is not in place to take the product beyond the proof-of-principle. 

It is not hyperbole to say ‘…a great product is 5 % determined by the technology and 95 % based on the commercialisation team that brings it onto the market, and sticks with the product through to adoption by the majority of the market...’

At ZP we have the mindset, technology, manufacturing, and network to put technologies onto the market, and so in the right environment we can support product beyond the development and manufacturing phases and into sales, marketing, and customer support.

Zimmer and Peacock are delighted to be featured in Craig Bank's review on measuring the pungency of chilli, see Craig's article and link to the next generation of  chilli sensor.

As part of the ZP Accelerator stack of technologies ZP has The ezPrism, an OEM hardware and electronics set, that clients that are 'deeply embedded' with ZP can leverage to get an application to market quickly.

At ZP we believe in our electrodes and our ability to collaborate with clients on the contract development and manufacture of their electrochemical biosensors and IVDs.

In a meeting today our CSO was able to quickly demonstrate to a client that our sensors are perfect for single drop analysis by pricking his finger and dropping a single  blood of blood onto the tip of the electrode.

At ZP we are passionate about our electrochemical biosensors. At ZP we understand that using electrochemical impedance spectroscopy as the mode of detection for electrochemical biosensing does not necessarily require gold sputtered interdigitated electrodes.

At ZP we are biased and so of course we recommend our gold screen printed electrodes for immunosensor type sensing.

In a world first ZP and PalmSens are hosting a joint webinar where we will be demonstrating live a PalmSens Sensit Smart in conjunction with a ZP biosensor. 

This free webinar is perfect for everyone interest in biosensors, the development of biosensors and the manufacture of biosensors.

As ZP opens Europe's largest full service contract development and contract manufacturing centre for electrochemical biosensors we are delighted to be flying the ZP flag. 

On this page we discuss the use of ZP pH Sensors with the PalmSens Sensit powered by Analog Devices.

At Zimmer and Peacock we strongly believe in people and the ability of a great team to change the world for all our benefits. This is why we are delighted that ZP Ltd has been certified by the United Kingdom Home Office to sponsor Skilled Workers.

This morning one of our engineers was driving to work, when they looked up onto the hill they saw  a new building with the ZP logo on it and took a picture.

Welcome to the newest building in the family

This week in the ZP Developer Zone Live Streaming Webinar we talked about cortisol biosensors and electronics for implantable biosensors.

The pea is the perfect electronics for electrochemical biosensors.

The biosensors of the future are wearable, implanted and point of need.

The pea from ZP is the perfect compliment to the next generation of  biosensor applications.

Click to see biosensors

ZP is an ISO13485 manufacturer with core competencies of: electrode design and fabrication, electrode manufacturing and electrochemistry.

At ZP we are expanding our electrode manufacturing capabilities through the occupation of a new 4000 square meter facility; the heart of our new facility are the production lines for electrodes for multiple electrochemical applications. In addition to support our expansion we are currently one of the largest sponsors of academic electrochemical research in the United Kingdom, with multiple PhDs and Masters students at: Swansea University, Plymouth University, Glasgow University, and with more in the pipeline.

Zimmer and Peacock are giving the first talk at Biosensors 2021; Dr Martin Peacock's talk is titled, 'The good, the bad and the ugly - a life in business'.

ZP is  a unique company as our raison d'etre is to get our clients and collaborators to the biosensor market.

If you want hear Martin's talk please register at Biosensors 2021.

PROBLEM SEVEN - There are many applications where the sample itself is very precious, hard to obtain or expensive. The ZP electrodes are perfect as there size means that a sample as small as one drop of blood will cover the electrodes as illustrated in the adjacent image, where a drop of the authors blood has been used to cover all three electrodes of a carbon 303.

PROBLEM EIGHT - There is a lack of customer support and bioelectrochemistry expertise among the manufacturers of screen printed electrodes, at ZP we have over come this though our free questions and answers forum, click image to find out more.

ABOUT SARISSA

Sarissa Biomedical was formed as a spin-out from Warwick University, that specialized in the development and production of novel biosensors for the measurement of neuroactive chemicals. 

The patents in the portfolio are listed below:

ZP is a very collaborative biosensor development and manufacturing business; as part of our collaborative nature we are supervising several Master Programs in collaboration with USN.

ZP has been collaborating on the development on smart phone applications and Cloud Databases for biosensor applications.

ZP has been collaborating on the development of sensors for the food and beverage industry.

A webinar focused on Biosensors, BioMEMS and MEMS for Agriculture, Aquaculture and Foods. This webinar has a particular focus for industries and academics in Vietnam, but registration is open to the rest of world. The webinar is presented by the University of South-Eastern (USN) Norway and Zimmer and Peacock AS.

Who should attend?

People interested in the development, manufacturing of BioMEMS and Biosensors, including those interested in collaborating with USN and ZP.

Bao Quoc Ta

Associate Professor

Faculty of Technology, Natural Sciences and Maritime Sciences, USN

At ZP we do receive a lot of enquires regarding our ability to develop and manufacture biosensors for COVID-19 and whether we 'can do it', the answer is 'of course we can', but in the specific case of COVID-19 the number of biosensors in development or are developed means that the market is now a little saturated, and the global capacity to manufacture biosensors is in addition fairly saturated. Further a lot of governments now have their testing strategies in place for this pandemic.

The advice from ZP is to accept that our planet is more connected than ever and so it is not to focus on COVID-19 biosensor development but rather focus on the next pandemic and help the World be be better prepared next time. At ZP we are encouraging the biosensors entrepreneurs to think further out, for example: Influenza, Ebola, Zika, Polio, etc.

If  you are interested in answering the question 'what's after COVID-19'  then please contact ZP to discuss our market analysis' group predictions for the next pandemic and how we can be better prepared.

At ZP we are a Cloud based paperless organisation, in line with our company structure which is a Dispersed Matrix Organization.

The eTools deployed at ZP are a  mix of proprietary and third party tools. If you are a client of ZP you can expect that:

• ZP will have all experimental records saved in electronic format
• ZP will have all electrochemical biosensor and manufacturing data saved in Djuli, our proprietary Cloud based system for electrochemical biosensor data
• ZP will be able to account for all efforts on your programme down to a 1 second resolution
• If you are enrolled on an ISO13485 contract development and manufacturing programme with ZP then the quality aspects of your programme are controlled within our eQMS system

ZP is an ISO13485 contract developer and manufacturer of biosensors. Along with our core focus on biosensor  and we are experienced in the entire technology chain from the biosensor, to the raw data and all the way to information displayed upon the smart devices.

At ZP we understand that the end purpose of a biosensor is not the biosensor itself, but rather the information and actions that can be taken from the biosensor data.

ZP has  the entire chain of products and services  going from the biosensor to the final actionable information, these include: biosensor, electronics, connectivity to the Cloud, calculations upon the Cloud, display of the information on the end user smart device.

The products and services from ZP includes:

• ZP has the largest range of off the shelf biosensors
• ZP is an ISO13485 contract developer and manufacturer of biosensors
• ZP is a developer and manufacturer of analogue and digital electronics
• ZP has an existing Djuli Cloud platform for receiving biosensor data 
• ZP is a certified iOS and Android developer

At ZP we love data and data science, in our buisness, our client programs and the markets we address we see that products, technologies and services are accelerating to market when supported by the data tactics and data strategies  implemented by the ZP Data Sciences Team.

One of the most important efforts in any biosensor data sciences effort is data cleaning; at ZP we clean biosensor data in the context of a full understanding  of the implications of what this data cleaning could mean to the quality of the data and the impact this cleaning can have upon the conclusions drawn from the data.

At ZP we are an ISO13485 contract developer and manufacturer of electrochemical biosensors and IVDs.

When project managing our customers' projects and programs we are  always applying Project Management Institute (PMI) principles, and so we are trained in the nuances of balancing the conflicting demands of: Good, Cheap and Fast.

The ZP Project Triangle asks the question, which combination of Good, Cheap and Fast is important to you:

• Good and Cheap, therefore the project will not be Fast.
• Good and Fast, therefore the project cannot be Cheap.
• Fast and Cheap, here the output can't be Good; in ZP's opinion this is the worst combination as it is not inline with our ISO13485 based philosophies.

Biosensors can offer:

• Quantitative data- the concentration of analytes.

• Longitudinal data – how concentration changes as a function of time.

• Spatial data – An array of sensor, or sensors placed within flows can give the spatial resolution of how an analyte such as pH changes both temporally and spatially. 

Quantitative data

The range of electrochemical biosensors suitable for monitoring the environment of cells has increased considerable in recent times.

Biosensors, including the ZP Glucose Sensors, provide a signal that is proportional to the analyte. In the figure below we show the signal as a function of glucose concentration, see Figure 1.0.0.

Longitudinal data

Biosensors can operate for extended periods, for example the glucose sensor from ZP has an operational life greater than 90 days, see adjacent image, and so ZP sees well designed sensors operating throughout the cell-based experiment.

Spatial data

Very recently biosensor arrays of nine biosensors haven been reduced to sensing areas less than 12 mm x 12 mm, see adjacent figure, and further miniaturization is also possible.

The biosensors from ZP can also provide spatial resolution, where an array of sensors provides a time course and spatial resolution of the analyte. The ZP biosensor array technology most matured in this respect is the ZP pH sensor arrays.

ZP takes a holistic approach to ISO13485 contract development and manufacturing of electrochemical biosensors including:

• Market research, analysis, and business case development
• Proof of principle studies
• Contract development of point of care devices and in field testing technologies
• ISO13485 Quality Management System consulting and development for biosensor development and manufacturing 
• Contract biosensor development
• Clean room processes and assembly 
• Clinical support and strategy
• Development and manufacturing of microfluidics, lab on a chip (LoC), total analytic systems (TAS)

The range of services and products from ZP reflect that we have to take a holistic view when engaging with a client on the subject of electrochemical biosensor and IVD development and manufacturing as biosensor development, biosensor manufacturing, quality, clinical approval, market acceptance are not mutually exclusive or isolated functions. 

The holistic philosophy at ZP imeans that we are able to support clients on each step to build a biosensor and IVD product and/or business.

At Zimmer and Peacock we are an ISO13485 contract manufacturer of electrochemical biosensors and in-vitro diagnostics. As part of services to our clients and collaborators we provide a range of services and products including screen printing of electrodes. 

At ZP we have off the shelf screen printed electrodes and we make custom screen printed electrodes, but we also take a pragmatic view on small volume prototyping. For small scale manufacturing we suggest rather than investing money and time into having customized screen printing services we encourage people to hand paint their electrodes

For those who want a more professional finish of electrodes we can supply stencils in addition to the biosensor and electrode paints.

ZP can custom fabricate a stencil, through which the scientist/engineer can paint our paints and inks onto a suitable such as PET, see below.

ZP will create a repeat of your sensor in a 100 mm x 100 mm sheet

Some fields benefiting from biosensors are:

• Food Industry - Sensors and Biosensors are finding their way into the Food and Beverage Industry, where they are use for Food Quality and Food Safety. These applications include the measurement of the hotness of food to the E. Coli in food.

• Agriculture - Sensors and Biosensors are finding their way into the Agricultural industry, which like many industries is moving to a more precise applications of chemical inputs such as nitrate fertilizers.

• Medical - Sensors and Biosensors have always been synonymous with medical and human health. The largest medical market for biosensors is self monitoring blood glucose (SMBG), where diabetics are able to monitor their blood glucose by testing capillary blood. At the time of writing this article continuous glucose monitoring (CGM) is rapidly growing and though the market is dominated by three vendors, new players such as Apple and Glucose are also trying to enter the market.

Biosensors are transducers that convert a biological event into an electrical signal. Biosensors were invented by Leyland Clarke in 1956. The first electrochemical sensors made by Clarke was an oxygen sensor, but the later addition of glucose oxidase turned the oxygen sensor into a glucose sensor.

The development and manufacture of biosensors is complex due to their inherent multi-disciplinary nature. A modern biosensor team will include engineers and scientists with backgrounds in: biology, chemistry, materials science, electrochemistry, electromechanical engineering, manufacturing engineering, regulatory affairs etc.

The materials used in biosensors are in four main categories:

• Enzymes - The commonly used enzymes are the oxidases, peroxidases, the dehydrogenases and the isomerase. These types of sensors are commonly interrogated by amperometry and/or voltammetry.
• Bioaffinity - The commonly used molecules here are: antibodies, aptamers, single stranded DNA/RNA nucleic acids, molecular imprinted polymers (MIPS). These types of sensors are commonly interrogated by amperometry and/or voltammetry.
• Ionophores - For the detection of ions such as sodium, potassium, chloride, calcium, ammonium etc, a corresponding ionophore exists. These types of sensors are commonly interrogated by potentiometry.
• Microbial - These are sensors where microbes are used to sense. These types of sensors are often based on electrochemical fuel cells, where the power out put of the microbial fuel cells is proportionate to the health of the microbial population, and so nutrients and/or toxins in the sample effect the power (signal) proportionally. 

Zimmer and Peacock – Biosensor and Medical Diagnostic Placement Opportunities in the UK and Norway

Zimmer and Peacock is a world leading biosensor development and manufacturing team located primarily in the UK and Norway, so we have placement opportunities across multiple sites for the right candidates. 

Our biosensors are used across a variety of applications from medical devices, precision farming, wearable biosensors and the Internet of Things, making this the perfect opportunity for someone who cares about making a difference to peoples’ livelihoods. At Zimmer and Peacock, we are partnering with academia and industry to ensure that there are enough good and commercially available sensors to meet the requirements of these new and growing markets. We innovate around our collaborators’ inventions to help bring ideas to market.

We are looking for highly motivated scientists with backgrounds in either biology, chemistry, material science or biomedical sciences to join our team in the production and testing of biosensors. You will collaborate with our production teams on the creation of biosensors, as well as data analysis and interpretation of the results. Alongside working with the production team, you will undertake independent working on report compilation and presentations for colleagues and clients.

Whilst the science background is important, we are more interested in you, your attitude and what you can bring to the table than necessarily the course you have taken so far. 

Zimmer and Peacock – Biosensor and Medical Diagnostic Placement Opportunities in the UK and Norway.

Zimmer and Peacock is a world leading biosensor development and manufacturing team located primarily in the UK and Norway, so we have placement opportunities across multiple sites for the right candidates.

Our biosensors are used across a variety of applications from medical devices, precision farming, wearable biosensors and the Internet of Things, making this the perfect opportunity for someone who cares about making a difference to peoples’ livelihoods. At Zimmer and Peacock, we are partnering with academia and industry to ensure that there are enough good and commercially available sensors to meet the requirements of these new and growing markets. We innovate around our collaborators’ inventions to help bring ideas to market.

We are looking for highly motivated engineering students from Plymouth University, across a spectrum of disciplines including, mechanical, electronic, biomedical, materials, etc., to join our team. You will need to be able to take a broad perspective to our work and be willing to understand the mechanical, electronic and biological elements of biosensors and invitro diagnostics.

You will collaborate with our engineers in the designing, testing and validation of prototypes and hardware, as well as data analysis and interpretation of the results. Alongside working with our engineers, you will undertake independent working on report compilation and presentations for colleagues and clients.

Whilst the engineering background is important, we are more interested in you, your attitude and what you can bring to the table than necessarily the courses you have taken so far. 

Whilst your academic background is important, we are more interested in you, your attitude and what you can bring to the table than necessarily the courses you have taken so far. 

Please complete the form below to apply.

Zimmer and Peacock has Digital Design/Animation Placement and Internship Opportunities in the UK and Norway.

Zimmer and Peacock is a world leading biosensor development and manufacturing team located primarily in the UK and Norway, so we have placement opportunities across multiple sites for the right candidates.

Our biosensors are used across a variety of applications from medical devices, precision farming, wearable biosensors and the Internet of Things, making this the perfect opportunity for someone who cares about making a difference to peoples’ lives. At Zimmer and Peacock, we are partnering with academia and industry to ensure that there are enough good and commercially available sensors to meet the requirements of these new and growing markets. We innovate around our collaborators’ inventions to help bring ideas to market.

We are looking for  highly motivated Arts and Humanities students from Plymouth University across a spectrum of disciplines including: Product Design, Animation, Graphic Design, etc., to join our team. You will collaborate with our Marketing team, using a variety of tools, to showcase Zimmer and Peacock and our products across multiple social media platforms. You will also undertake independent working on your designs, posts and presentations for colleagues and clients.

Whilst your academic background is important, we are more interested in you, your attitude and what you can bring to the table than necessarily the courses you have taken so far. 

Please complete the form below to apply.

ZP is the world leading ISO13485 contract developer and manufacturer of electrochemical biosensors and IVDs, including the manufacture of screen printed electrodes.

At ZP we take a pragmatic view and though we think the potentiostats that we make and/or sell are the best we are also appreciative that engineers and scientists like to build their own instruments.

In the adjacent table we have compared and contrasted the low cost/open source/free potentiostats and linked tothem below.

In our opinion the best lower cost potentiostat on the market at the time of writing this article is the Sensit Smart, which is available from ZP, but we have also linked to the open source potentiostats.

ZP are supporters of KTP.

The Knowledge Transfer Partnership (KTP) scheme helps businesses in the UK to innovate and grow. It does this by linking them with an academic or research organisation and a graduate.

A KTP enables a business to bring in new skills and the latest academic thinking to deliver a specific, strategic innovation project through a knowledge-based partnership.

The academic partner (known as the Knowledge Base) will help to develop the project, provide academic input and recruit a suitable graduate, known as an associate. They will act as the employer of the associate, who then works at the business for the majority of the project.

The scheme can last between 12 and 36 months, depending on what the project is and the needs of the business.

At ZP we truly understand our biosensors and we are happy to share our knowledge with the biosensor development community.

This week our head of production was testing a batch of pH sensors when he noticed that the sensitivity ws 59 mV/pH. This was immediately brought to the attention of our CSO as it is rare that the performance of an ion sensitive electrode such as a pH electrode are exactly in line with theory.

At Zimmer and Peacock we have a range of gold for electrodes for many applications including biosensors.

The gold electrodes we manufacture include:

• Low temperature screen printed gold
• High temperature screen printed gold
• PCB gold
• Vapor deposited gold on glass
• Vapor deposited gold on polymer

ZP is the only ISO13485 manufacturer of electrodes with electrochemistry at our core so we are able to characterise the electrodes that we manufacture.

Zimmer and Peacock is the World's Leading ISO13485 contract developer and manufacturer of electrochemical biosensors.

As part of our mission statement ZP is supporting the wider biosensor developer community, and as part of this commitment we are match funding grants from the Analytical Chemistry Trust Fund.

Upon our agreement to collaborate with you, and if you apply for and receive funding from the Analytical Chemistry Trust Fund to come and train at one of ZP's UK facilities for a 3 month period, then ZP will match fund your grant.

This support is only open to members of the ZP Developers Zone.

Click here to see fund details.

On this page you can find multiple reference resources for using the Sensit Smart, and how the Sensit smart integrates with ZP Biosensors screen printed electrodes and bio-sensing technologies. 

Glucose sensing on the smartphone.

Analysis of caffeine, coffee and energy drinks.

pH measuring with Sensit Smart

potassium measuring with Sensit Smart

Module 2B1 - Introduction to Generation One Glucose Sensors

Module 2C2 - Introduction to the Cyclic Voltammetry Analysis of Red and White Wine

At ZP we have the largest online range of technologies for continuous glucose monitoring technology (CGM) developers.

As part of our characterization of these technologies we have been continuously testing some of our CGM sensors and changing the temperature in order to understand the coefficient of temperature on the sensor.

At ZP we have the largest online range of technologies for continuous glucose monitoring technology (CGM) developers.

As part of our characterization of these technologies we have been continuously testing some of our CGM sensors on our screen printed platform, at the time of writing we are 93 days into continuous use.

At ZP we understand that the biomolecules at the heart of the ZP electrochemical glucose biosensors are intrinsically robust and hence why the sensors have such longevity. 

ZP is an ISO13485  contract developer and manufacturer of electrochemical biosensors and in-vitro diagnostics (IVDs), as part of our accelerating growth we are now expanding our clean room capacity.

Welcome to the 3D printed microfluidic solutions page from Zimmer and Peacock On this web page we have brought together the information from Zimmer and Peacock regarding printing microfluidic solutions for biosensor developers.

In order to fabricate these 3D printed biosensors you will to follow the three steps below.

You will require a ZP Hyper Value electrode, we recommend starting with a pack of 200 screen printed electrodes (SPE), part number ZPS HYP-000-00150. Please click the adjacent image.

You will require the ZP adhesives for screen printed electrodes.

You will require a 3D printable STL file.

ZP has a large number of academic collaborations and we are delighted when the results are excellent.

In a recent collaboration with Heriot Watt University, the ZP and HWU team have been developing  a sensor capable of spatially resolving both  differences and gradients of pH. 

FREE COURSES

To access free courses on ZP academy please search using the search term 'free' by clicking the ZP Academy logo here.

FREE TECHNICAL SUPPORT AT ZP DEVELOPERS ZONE:

To access free advice from ZP follow these three steps

• STEP ONE - Join the ZP Developers Zone.
• STEP TWO - Post your question in the forum.
• STEP THREE - Watch our live webinar at 8 AM  every Thursday and 8 PM every Sunday London time where we answer questions from the forum during a live streaming webinar. The webinar is saved and is available on YouTube after the live streaming.

PRIVATE CONSULTATION

For many commercial clients or where the questions require in depth analysis ZP offers private consulting.

ZP is an ISO13485 certified developers and manufacturers of electrochemical biosensors and IVDs.

The substrates we manufacture upon include: silicon wafers, ceramic, PET, glass, card, PCB  and paper.  At ZP we take a pragmatic view on which substrate we manufacture and chose the material most suitable for the application. 

One of the materials that is popular at the moment is paper, and so at ZP we are able to print our designs onto paper as the fabrication onto PET and ceramic is fairly straightforward to translate onto paper. ZP advises that you can go onto paper if there paper itself offers a material property that is useful to the final application, we make this comment as you should not move to paper simply because of a perceived cost saving. 

THE COST ARGUMENT FOR PAPER

The argument that paper is the only material that offers low cost products is diminished when you consider that the screen printed hypervalue electrodes from ZP are:

• 99 cents each in packs of 200,
• 50 cents when in packs of 10,000
• 25 cents when in packs of 100,000
• 5 cents in packs of 10,000,000.

This example demonstrates a common point with manufactured goods, which is the higher the production volume the lower the cost. As can be seen from the example above the cost of the SPE can be reduced to 5 cents and below by simply increasing the production volume.

THE FOUR  IMPORTANT FACTORS THAT DRIVE COST OF SPE ARE

Below we have listed four factors that can drive the cost of screen printed electrodes/SPE/biosensors, it should be noted that the materials of construction are not listed because materials of construction as an important parameter is outside of the top four parameters when considering what drives cost.

1) QUANTITY - How many screen printed electrodes/biosensors do you require?

2) QUALITY - What is the quality you require?

3) SIZE OF SPE/Biosensor - You can often reduce the cost of a biosensor or screen printed electrode by 75 % by halving the length and width of the design.

4) STANDARD versus CUSTOM DESIGN - Customization is always more expensive, than an off the shelf product. In a customization program you often have a team of R and D engineers and scientists involved and so the cost of their efforts have to recouped through the price of the products and programme.

QUANTITY 

Commercial screen printed electrodes and biosensors are often sold at a price that is proportional to the volumes sold. When a product is ordered in the 10s and 100s the manufacture of the product has a high administration cost to ship a relatively small number of items and so many manufacturers and distributers have a pricing accordingly. The ZP hypervalue screen printed electrodes show a price range form 99 cents to 5 cents based on the number of screen printed electrodes required.

QUALITY

A common practice in the manufacture of screen printed electrodes is to manufacture and ship. At ZP we manufacture, we electrochemically test and then we ship. ZP is the only ISPO13458 contract developer and manufacturer of screen printed electrodes that electrochemically tests our screen printed electrodes to ensure that they are electrochemically functional before shipping.

SIZE OF SPE/Biosensor

The simplest way of reducing the cost of many products is to reduce their size in doing so you can often increase the production rate. At ZP we imagine that our clients are truly wanting to get to market and so our standard products such as the hypevalue screen printed electrodes are sized so that they can make sense when produced in sufficient manufacturing volumes. How size can impact price of biosensors and screen printed electrodes can be seen in the adjacent button.

STANDARD VERSUS CUSTOM DESIGN

Customization is always more expensive, than an off the shelf product. In a customization program you often have a team of engineers and scientists involved and so the cost of their efforts have to recouped through the price of the products and programme.