Below is the rolling news feed from Zimmer and Peacock. Our news feed represents that Zimmer and Peacock is a fast moving active company with lots of well-directed activity.

Thu

15

Apr

2021

ZP builds new class 7 clean room

ZP is an ISO13485  contract developer and manufacturer of electrochemical biosensors and in-vitro diagnostics (IVDs), as part of our accelerating growth we are now expanding our clean room capacity.


Wed

14

Apr

2021

3D printed microfluidics

Welcome to the 3D printed microfluidic solutions page from Zimmer and Peacock On this web page we have brought together the information from Zimmer and Peacock regarding printing microfluidic solutions for biosensor developers.

 

In order to fabricate these 3D printed biosensors you will to follow the three steps below.


STEP ONE

You will require a ZP Hyper Value electrode, we recommend starting with a pack of 200 screen printed electrodes (SPE), part number ZPS HYP-000-00150. Please click the adjacent image.

STEP TWO

You will require the ZP adhesives for screen printed electrodes.

STEP THREE

You will require a 3D printable STL file.


Tue

13

Apr

2021

pH spatial resolution

ZP has a large number of academic collaborations and we are delighted when the results are excellent.

 

In a recent collaboration with Heriot Watt University, the ZP and HWU team have been developing  a sensor capable of spatially resolving both  differences and gradients of pH. 

 

The ZP team have been able to miniaturize pH sensors and place them within an area smaller and 10 mm x  10 mm. There is a total of nine pH sensors in a 3 x 3 array.

 

At the time of writing this note the HWU engineer has programmed a nice interface where the pH at individual 'pixels' can be seen through the judicial use of color coding.


Tue

13

Apr

2021

4 mm diameter carbon working electrode from ZP

In this note we discuss ZP's current Hyper Value electrode with a rectangular working electrode, and we discuss a proposed variant with a 4 mm diameter circular electrode.

 

At Zimmer and Peacock we are biased and so of course we are big fans of our ZP Hyper Value Electrodes, which can be seen in the adjacent panel.

 

At ZP we deliberately make our electrodes rectangular, for the the reason covered in our article 'Hacking the Glucose Sensor'. 


4 mm working electrode configuration

At ZP we have a very different philosophy to many manufacturers of screen printed electrodes, in that at ZP we will do customization work for clients, but we also engage in detailed consultative conversations so that the client can benefit from the decades of biosensor development experience within the ZP team.

 

From multiple conversations we appreciate that in the research phase of a commercial programme or in academic research then a lot of functionalization of screen printed electrodes is performed using hand pipetting; therefore ZP is next looking to develop our ZP Hyper Value Electrode in  a circular working electrode.

 

The ZP plan is to fabricate our ZP Hyper Value Carbon Screen Printed Electrodes but with a circular working electrode, see adjacent images.

 

If you are interested in being a recipient of some of the first 4 mm circular screen printed electrodes please click the adjacent button.


Sat

27

Mar

2021

Free questions and answers with ZP

If you have a technical question for ZP then you have three routes to finding your answers: ZP Academy, ZP Developers Zone or Private Consulting.

 

We offer free advise through our ZP Developers Zone or there are free courses on the ZP Academy. if you would rather have a private discussion we do offer private consultancy services.


FREE COURSES

To access free courses on ZP academy please search using the search term 'free' by clicking the ZP Academy logo here.


FREE TECHNICAL SUPPORT AT ZP DEVELOPERS ZONE:

 

To access free advice from ZP follow these three steps

  • STEP ONE - Join the ZP Developers Zone.
  • STEP TWO - Post your question in the forum.
  • STEP THREE - Watch our liver webinar at 8 AM London time every Thursday where we answer questions from the forum during a live streaming webinar. The webinar is saved and is available on YouTube after the live streaming.


PRIVATE CONSULTATION

For many commercial clients or where the questions require in depth analysis ZP offers private consulting.


Thu

25

Mar

2021

Paper based biosensors

ZP is an ISO13485 certified developers and manufacturers of electrochemical biosensors and IVDs.

 

The substrates we manufacture upon include: silicon wafers, ceramic, PET, glass, card, PCB  and paper.  At ZP we take a pragmatic view on which substrate we manufacture and chose the material most suitable for the application. 

 

One of the materials that is popular at the moment is paper, and so at ZP we are able to print our designs onto paper as the fabrication onto PET and ceramic is fairly straightforward to translate onto paper. ZP advises that you can go onto paper if there paper itself offers a material property that is useful to the final application, we make this comment as you should not move to paper simply because of a perceived cost saving. 

 

THE COST ARGUMENT FOR PAPER

The argument that paper is the only material that offers low cost products is diminished when you consider that the screen printed hypervalue electrodes from ZP are:

  • 99 cents each in packs of 200,
  • 50 cents when in packs of 10,000
  • 25 cents when in packs of 100,000
  • 5 cents in packs of 10,000,000.

This example demonstrates a common point with manufactured goods, which is the higher the production volume the lower the cost. As can be seen from the example above the cost of the SPE can be reduced to 5 cents and below by simply increasing the production volume.

 

THE FOUR  IMPORTANT FACTORS THAT DRIVE COST OF SPE ARE

 

Below we have listed four factors that can drive the cost of screen printed electrodes/SPE/biosensors, it should be noted that the materials of construction are not listed because materials of construction as an important parameter is outside of the top four parameters when considering what drives cost.

 

1) QUANTITY - How many screen printed electrodes/biosensors do you require?

 

2) QUALITY - What is the quality you require?

 

3) SIZE OF SPE/Biosensor - You can often reduce the cost of a biosensor or screen printed electrode by 75 % by halving the length and width of the design.

 

4) STANDARD versus CUSTOM DESIGN - Customization is always more expensive, than an off the shelf product. In a customization program you often have a team of R and D engineers and scientists involved and so the cost of their efforts have to recouped through the price of the products and programme.


QUANTITY 

Commercial screen printed electrodes and biosensors are often sold at a price that is proportional to the volumes sold. When a product is ordered in the 10s and 100s the manufacture of the product has a high administration cost to ship a relatively small number of items and so many manufacturers and distributers have a pricing accordingly. The ZP hypervalue screen printed electrodes show a price range form 99 cents to 5 cents based on the number of screen printed electrodes required.


QUALITY

A common practice in the manufacture of screen printed electrodes is to manufacture and ship. At ZP we manufacture, we electrochemically test and then we ship. ZP is the only ISPO13458 contract developer and manufacturer of screen printed electrodes that electrochemically tests our screen printed electrodes to ensure that they are electrochemically functional before shipping.


SIZE OF SPE/Biosensor

The simplest way of reducing the cost of many products is to reduce their size in doing so you can often increase the production rate. At ZP we imagine that our clients are truly wanting to get to market and so our standard products such as the hypevalue screen printed electrodes are sized so that they can make sense when produced in sufficient manufacturing volumes. How size can impact price of biosensors and screen printed electrodes can be seen in the adjacent button.


STANDARD VERSUS CUSTOM DESIGN

Customization is always more expensive, than an off the shelf product. In a customization program you often have a team of engineers and scientists involved and so the cost of their efforts have to recouped through the price of the products and programme.


Tue

16

Mar

2021

The problem of connectors with screen printed electrodes

Zimmer and Peacock are the only company that wafer maps their off-the-shelf screen printed electrodes before shipping.

 

Wafer mapping is ZP's process of taking a sample of screen printed electrodes from every manufacturing batch and electrochemically  testing them to ensure they are within specification. This means that our clients find our electrodes both repeatable and of course functional.

 

It is this testing before shipping  that gives us the confidence in helping clients to trouble shoot their problems; in the adjacent image we show some cyclic voltammetry data gathered by a client, where their actual result was a  long way from our expected result. In this case we were very confident that the problem wasn't the ZP SPE but the client's experimental set-up. In this case the route-cause of their problem was a 'bad' connector.

 

At ZP we do use the SPE 2.54 mm pitch connector, which is the standard for off-the-shelf SPEs, but not all connectors are made to the same standard, so if you are purchasing a ZP biosensor or ZP SPE we do strongly suggest that you purchase our ZP connector below.


7 mm hypervalue SPE/biosensor connector

Connector for ZP 7 mm SPE adapts to 3 mm banana plugs

250,00 €
Add to Cart
  • Available
  • Generally ships within 2-4 weeks

Sat

13

Mar

2021

Detecting vitamin C/ascorbic acid in orange juice

At ZP we know that electrochemistry is the most robust science for the everyday detection of chemical and biological molecules. 

 

As part of ZP's innovative approach  we offer a range of courses that are free to our customers and collaborators including a module on the measurement of vitamin C/ascorbic acid in orange juice.

Click the course image below to see our orange juice module.


Sun

07

Mar

2021

Resources for Academic Biosensor Developers

Zimmer and Peacock have free resources for the biosensor development community, every Thursday we have the ZP Live streaming which is available to our ZP Developer Zone Members and we have our ZP Academy where we host some free courses for the biosensor development community.

 

Please click the images to access the services.


Fri

05

Mar

2021

Microwell features

Zimmer and Peacock are expert at adding features to the surfaces of screen printed electrodes to act as barriers or microfluidics.


Thu

04

Mar

2021

Roughness of screen printed electrodes

The quality of ZP's screen printed electrodes is due to the technical skills of the ZP Team and the range of the technical instruments we are able to call upon.

 

This week the ZP team has been determining the print thickness and the arithmetic surface  roughness using our profilometer to measure print thickness and the print roughness.


Tue

02

Mar

2021

ZP's Vision and Mission

ZP's Vision is to do good.

 

The ZP Mission is to leverage our passion for biosensors to improve outcomes for our global community. The ZP story starts with biosensors, but we are at every stage from sample to  final actionable information, with our focus on health, the environment and food production .

 

The  values upon which we stand are:

 

 

1) VALUE ONE - Follow good environmental, society and governance principles.

 

2) VALUE TWO - Quality at the heart  of what we do.

 

3) VALUES THREE - Provide great jobs, great technology and greater opportunities for our wider community.

Sun

28

Feb

2021

QR codes onto screen printed electrodes and biossensors

Zimmer and Peacock is the world's only ISO13485 contract manufacturer of biosensors, screen printed electrodes and IVDs who can individually label each product with a unique QR code.

 

These QR codes can carry a range of data, including: manufacturing data, calibation data, expiration data etc.

 

Please contact ZP to find out how we can go beyond manufacturing.


Thu

11

Feb

2021

Take a virtual tour of new 4000 square meter ISO13485 facility

Zimmer and Peacock is the World's fastest growing ISO13485 contract development and manufacturing company of electrochemical IVDs and biosensors. 

 

Please take a virtual tour of the new dedicated 4000 square meter  dedicated manufacturing facility. 

Thu

11

Feb

2021

ZP opens new 4000 square meter ISO13485 facility

Alongside our recently awarded ISO13485 certification for the contract development and manufacturing of electrochemical biosensors and IVDs, ZP is delighted to announce an expansion into a new 4000 square meter facility.

 

ZP will retain it's existing Norwegian facility assets, and so the access to this dedicated manufacturing building will allow us to house the considerable CAPEX investment in manufacturing technologies for electrochemical IVDs and biosensors that are being made in 2021.

Mon

08

Feb

2021

Proof of principle (POP) studies at ZP

A proof of principle (POP) study at ZP is a short programme, typically about 111 hours of effort spread over 3 months, where ZP takes the work and understanding already with our collaborates and translates it onto our ZP platforms.

 

The purpose of the work is to bring the work from its current status and move it onto a platform that ZP sees can be manufactured within our ISO13485 facility. The client and ZP are not obliged to perform later phases after this POP phase.

  

The understanding that the client has regarding their electrochemical assay or biosensor the can include:

 

1) Practical work already under taken.

 

2) Academic papers from the literature.

 

3) Patents licensed/owned by the collaborator.


The stages in a proof of principle programme

The effort in a ZP proof of principle programme (PoP) is a time and materials effort and ZP will work within the constraints of the budget of approximately 111 hours.

 

In a POP programme ZP will:

 

1) STEP ONE - Perform a tech transfer or discussion with the client to understand the status of the technology and learn all the tips, tricks and anecdotes that the client can give to make ZP's efforts as efficient as possible.

 

2) STEP TWO - ZP will suggest one or more first small pieces of work within the POP, which we will discuss with the client before proceeding. These suggestions are based on where the technology is today and where does the technology need to be in terms of the market/clinical  requirements. ZP will work through the work to see which of the ideas both works and is commercially viable. The number of ideas worked upon is constrained by the budget.

 

3) STEP THREE - ZP will give  online update meetings where we will give a presentation on the work done and the results so far. ZP is happy to receive comments and feedback from the clients.

 

Please note that ZP will build a presentation for the client as we work, in addition ZP can produce reports, procedures etc. All work can be done within the constraints of the budget.

Sat

30

Jan

2021

ZP Hyper Value - Screen Printed Electrodes

Zimmer and Peacock has a series of training and educational videos that are designed to integrate directly with our ZP Hyper Value Electrodes. In this box are 200 carbon screen printed electrodes, which are exactly the ones featured in the training modules on the ZP Academy.

 

On the back of the box is a promo-code that allows free access to the relevant training and educational modules on the ZP Academy; these courses are listed below.

 


ZP Hyper Value Screen Printed Electrode - Pack of 200 Screen Printed Electrodes

 

200 screen printed electrodes in the box

198,00 €
Add to Cart
  • Available
  • Generally ships within 2-4 weeks
Sensit Smart and ZP Hyper Value Screen Printed Electrode - Pack of 200 Screen Printed Electrodes and Sensit Smart

 

200 screen printed  carbon electrodes in the box and a one Sensit Smart

988,00 €
Add to Cart
  • Available
  • Generally ships within 2-4 weeks
Sensit Smart

 Sensit Smart

855,00 €
Add to Cart
  • Available
  • Generally ships within 2-4 weeks

The ZP Academy contains training modules and courses for developers, scientists, engineers and entrepreneurs who want a flying start in their understanding of electrochemical sensors. The courses below specifically require the ZP Hyper Value Screen Printed Electrodes and the Sensit Smart which can be bought above.


Module 2C2 - Introduction to the Cyclic Voltammetry Analysis of Red and White Wine

In this module we describe a simple kitchen experiment for the analysis of wine, using the ZP Hyper Value Screen Printed Electrode and PalmSens’ Sensit Smart potentiostat. 

All chemicals used in this experiment were purchased from the local Grocery Store.

 

This note and the accompanying video demonstration are intended to give a quick and easy introduction to the Sensit smart, screen printed electrodes and a first quick start in wine analysis. 

There is an interest in the analysis of wine from a number of perspectives, including:

 

• Qualification/Authentication of Wine – The chemical profile of wine can be distinct and dynamic with time as the wines ages, especially with red wines. The concentration of molecules such as proanthrocyanidins, condensed tannins and anthocyanins change as the wine ages .

• Quality control through Quantification of Total Phenols – The total phenols in red/white/young/aged wines is variable, but the total phenols in wine can be measured by using electrochemical analytical techniques .


Module 2H2 - Introduction to the Cyclic Voltammetry Orange Juice

An introduction module to the analysis of vitamin C/ascorbic acid in orange juice using ZP Hyper Value Screen Printed Electrodes (SPE) and the PalmSense Sensit Smart Potentiostat, with ADI on board.

 

In this note and accompanying video we describe a simple kitchen experiment for the analysis of orange juice using the ZP Hyper Value Screen Printed Electrode and PalmSens’ Sensit Smart potentiostat.

 

All chemicals used in this experiment were purchased from the local Grocery Store.


Module 2I2 - Introduction to the Cyclic Voltammetry Coffee and Red Bull

An introduction module to the analysis of caffeine in coffee and Red Bull/energy drinks  using ZP Hyper Value Screen Printed Electrodes (SPE) and the PalmSense Sensit Smart Potentiostat, with ADI on board.


Module 2B1 - Introduction to Generation One Glucose Sensors

This module is provided free to customers of ZP and/or PalmSens who have purchased the ZP Glucose sensors and Sensit Smart Potentiostat.


Fri

22

Jan

2021

Zimmer and Peacock - CheapStat

At ZP we like to support the biosensor development community, we are sometimes asked to help students and makers develop potentiostats.

 

In the buttons below we link to electronics and screen printed electrodes to inspire biosensor developers. We also link to the CheapStat an open source potentiostat.

Fri

22

Jan

2021

ECG technologies @ZP

Zimmer and Peacock is an ISO13485 certified company for the design and manufacture of medical products.

 

On this page we link to technologies and materials we see as relevant to ECG/EKG development and manufacture

Tue

19

Jan

2021

ZP - seeking ambitious clients - ZP-C2

Zimmer and Peacock is reaching out among our existing clients and seeking new ambitious clients to part of our next wave of expansion. 

 

As we expand into a new facility we can add 4000 square meters on top of our current Norway infrastructure, we are therefore welcoming our clients to potentially co-locate with us as part of our client incubator lab and contract manufacturing. 

 

The building has have the following amenities:

 

1) State of the art boardroom for online conference calls and face-to-face meetings.

 

2) Excellent connectivity to Oslo

 

3) Lockable Client Offices

 

4) Cleanrooms

 

5) ISO13485 Manufacturing Hall

 

6) Lecture Theatre

 

7) Laboratory

 

8) Dedicated Dining Hall

 

9) Catered Commercial Kitchen

 

10) Manned Reception

Please contact ZP to explore this opportunity to engage more closely with the World's leading ISO13485 contract developer and manufacturer of electrochemical biosensors and medical diagnostics.


Tue

19

Jan

2021

USN Industrial Masters @ZP

 Zimmer and Peacock AS (ZP AS) are sponsors of the Industrial Master of Science Programme at USN - Micro and Nano System Technology, and is Norway's fastest growing biosensor and in-vitro diagnostic company. Head-quartered in Horten Norway, our team engages with clients and collaborators from Australia to California.

 

 

 

USN Industrial Masters @ZP

The USN Industrial Masters at ZP AS means you will work between USN and ZP AS. When at ZP AS you will be embedded within an international  team helping us to fulfill our mission to develop electrochemical biosensing systems that can positively impact society, our applications include: health, wellness, food and beverage, agriculture, aquaculture, environmental and process control.

The mission at ZP is to focus on the biosensors required for the internet of things (IoT) revolution, but to tackle the hard to develop sensors for molecules, bacteria and viruses. As part of our team engineers and scientist work across disciplines including: electronics engineering, mechanical engineering, biosensing engineering, chemistry,  microbiology, molecular biology, firmware coding, data-sciences and Cloud solution development.

Though our scientists and engineers have specific subject matter expertise, they  apply their skills within a multi-disciplinary team and have the satisfaction that all the efforts at Zimmer and Peacock AS lead to products on the market, that make  a direct difference to our world.


Mon

18

Jan

2021

Hiring USN trained Microfabrication Engineer

As  part of our continuing close relations with USN, ZP is looking to recruit a full time or part time post-graduate students/graduate students, who have gained a considerable degree of practical training within the  USN clean room facility.

 

You must be:

 

  • A USN graduate or currently studying at USN
  • You are at a senior level in regard to your experience and time spent within the USN clean room
  • You must be ready to work now, either  part-time or full-time

 

 DETAILED DESCRIPTION

 

Micro-fabrication Engineer

 

Micro-fabrication Engineer Job Responsibilities:

  • Micro-fabrication within cleanroom environment using dry etching machine, baking oven, sputter coating machine, thermal evaporation and copper plating machine.
  • Following existing microfabrication work instruction and possibility improvement of the current fabrication process.
  • Reporting fabrication process and drafting work instruction

Essential attributes:

  • More than two years’ experience in microfabrication.
  • More than two years’ experience of MEMS device design
  • Experience of bulk micromachining and fabrication processes with multiple stages of photolithography, dry etching, wet etching, baking, metal sputtering and metal plating, gained through working in a cleanroom environment.
  • Experience of using SEM and EDX to characterise fabricated device.
  • Ability to establish and develop new cleanroom processes.
  • Ability to present work at technical meetings.
  •  Ability to write work instruction.
  • Comfortable working unsupervised after initial training

 

 

 

Desirable attributes: 

  • Cross discipline working to identify potential process and device improvements
  • Ability to work in an interdisciplinary project team

 

 

 

Please complete this form to register interest.


Tue

12

Jan

2021

The Pursuit of Noninvasive Glucose - Hunting the Deceitful Turkey

For anyone working on a continuous glucose monitoring technology, whether implantable, trans-dermal, minimally invasive or even noninvasive then please do read 'The Pursuit of Noninvasive Glucose - Hunting the Deceitful Turkey' by John L. Smith.  You really can't claim to be in the CGM club until you have read this book.

 

At ZP we have been checking back into this book for about 15 years and we will often recommend it to others, especially those working on noninvasive glucose technology.

 

We have linked to the book in the buttons below and have included a button to ZP resources for anyone interested in CGM development.


Sun

10

Jan

2021

Gold electrodes for COVID-19 biosensor developers

At ZP we receive  a lot of enquires about gold electrode and their use as biosensors.

 

On this page we provide links specifically  for those wishing to develop a COVID-19 biosensor upon our gold electrodes, please see the buttons below.



Please click this button to see a discussion on cleaning gold screen printed electrodes.


Zimmer and Peacock is the only company that electrochemically characterises its screen printed electrode as part of the manufacturing process.


We have a resources page for people wishing to form a self-assembled monolayer on a gold electrode.


Sun

10

Jan

2021

Gold electrodes for impedance biosensors

At ZP we receive  a lot of enquires about gold electrode and there use as biosensors, along with the use of impedance spectroscopy to  read the sensor. Therefore  to help developers we have put this resources page together.


If you intend to use impedance measurements with gold electrodes then please watch this video.


Please click this button to see a discussion on cleaning gold screen printed electrodes.


Zimmer and Peacock is the only company that electrochemically characterises its screen printed electrode as part of the manufacturing process.


We have a resources page for people wishing to form a self-assembled monolayer on a gold electrode.


The print thickness of our gold screen printed electrodes can be found here.


The resistance of our  gold screen printed electrodes can be found here.


Wed

06

Jan

2021

FAQ for interns

At ZP we do recruit and train interns, here are some FAQs that we are sometimes asked.

FAQs

 

Is the start date same for all placement holders?

No, the start date varies for different candidates based on a skill-based segregation that we have made post assessment.

 

Base in Norway and UK?

We have our offices and labs in Horten, Norway.

We have our offices and labs in several locations in UK (Royston, London, Wolverhampton). The location for the candidates’ placement in UK is TBD.

 

How long would I be working in Norway?

The length of stay will be 3 months at a time alternated between Norway and UK throughout the placement.

The first training round will take place in Norway, wherein you will spend 3 months being trained and working in the Horten labs.

Then you will return to UK and spend the next 3 months working in a lab in the UK.

This cycle will continue through the placement period and the candidate is responsible for figuring out any visa requirements, although we may be able to provide some advice.

 

What costs will be covered by the company and what costs do we have to cover?

As per our company policy, we will cover only the cost of travel between UK and Norway (Flights, trains, bus, etc.).

All other costs have to be covered by the student. This includes visas, food and accommodation. If the university has a budget for covering this, you may ask or apply for it.

 

Is there accommodation readily available?

Yes, we will provide accommodation for the placements at a nominal rent.

If for some reason you choose not to stay at the accommodation provided by the company, it will be the candidate’s responsibility to manage their own accommodation.

The accommodation is a unisex (mixed-gender) house-share with individual rooms.

 

Are there other students that I will be working alongside in this placement?

Yes, there will be other students from your own and other universities working at ZP at the same time as you.

 

Can I change my start date?

This is not preferable as we will have to swap you over with another candidate, so this will be entertained if the circumstances can be explained and are considered essential.

 

What are the hours I will be working for?

The normal working hours are 9am-5pm with a break as per the government requirements but you can be requested to stay longer if required on certain days, but not extensively.

 

We do not offer overtime pay.

Mon

04

Jan

2021

<5 min COVID-19 Breath Test

Congratulations to Exhalation Technology for their less than 5 minute breath test for COVID-19.

 

The Exhalation team's clinical testing has shown amazing Clinical  sensitivity.


Thu

31

Dec

2020

ZP Screen printed electrode holder

ZP is delighted with these screen printed electrode (SPE) holders designed for our ZP biosensors and ZP screen printed electrodes.


Mon

28

Dec

2020

Tools for biosensor entrepreneurs

ZP is the world's leading independent ISO13485 contract developer and contract manufacturer of electrochemical biosensors and electrochemical in-vitro diagnostics. Therefore we are very used to working with start-ups and entrepreneurs. 

 

Below we have posted videos, links and materials that we have made specifically with biosensor entrepreneurs in mind.

 

If you are an entrepreneur with an electrochemical biosensor idea please don't hesitate to contact ZP.


Wed

23

Dec

2020

Chloride resilient formulation for silver/silver chloride reference electrodes

In the adjacent data we show the data screen printed silver/silver chloride electrode treated with ZP's chloride resilient formulation.

 

The intention of the chloride resilient formulation is to make the reference electrode less sensitive to chloride, which is useful in applications where the chloride is otherwise a variable.

raw data
chloride resilient raw data.xlsx
Microsoft Excel Table 39.5 KB

Fri

18

Dec

2020

ZP is hiring senior scientists and/or senior engineers

ZP is looking to hire senior scientists and/or senior engineers. 

 

In the first instance you will be working from our ZP AS site in Horten Norway, though you can expect to work both from London UK and Norway.

 

Technical positions at ZP are always fun and demanding, so you need to feel that you are world class, self motivated, a problem solver and a team player.

 

ZP has deliberately not specified your technical background as we find senior  scientists and engineers are not defined by their formal training, but rather by their wiliness to learn and self-educate through their careers. You can expect that you will be working on programmes where electrochemical biosensors is at the heart of the technology.

 

At ZP our unique expertise is electrochemical biosensors, so experience with this technology is an advantage, and if you would like to get a sense of our core science then please click the video link below.

 

If you are interested in finding out more please use the apply button below, and follow us on social media to see future opportunities.


Wed

16

Dec

2020

Working hard in the ZP Biosensor Labs

At ZP, our hardworking team  are constantly developing, manufacturing and shipping biosensors.

 

Wed

16

Dec

2020

Electroplating resources

Zimmer and Peacock has put together a resources pages around electroplating for medical devices. Please read more.


Wed

16

Dec

2020

Fully characterized screen printed electrodes

Zimmer and Peacock has had the working electrode of our hyper value screen printed electrode characterized by microscopy, please read more.


Tue

08

Dec

2020

FAQs on ZP pH sensors

At ZP we do get enquires about our electrochemical pH sensors, so we have made this page to answer some more FAQs.

 

 

QUESTION ONE  -  How many hours of continual use in simple aqueous solutions at pH 3-5 could the printed sensors withstand before significant degradation?

 

QUESTION TWO  -  How long would the sensor lifetime be in complex bio-fluids with additional ions (eg Na+, K+)?

 

QUESTION THREE - Can the sensors be reused (eg with a suitable washing step) or would you recommend one-time use?

 

QUESTION FOUR -  Approximately how many bending cycles can the pH sensor withstand?


Mon

07

Dec

2020

Medical Wearables

Zimmer and Peacock are the World Leader in contract development and manufacturing of wearables.

 

This week we are exhibiting at  Medical Wearables 2020.


Sat

05

Dec

2020

Internships at ZP

At Zimmer and Peacock we do offer internships, to see announcements on when we have internships available please do follow us on social media.

 

If you would like to join ZP on a permanent basis then the internship programme is a good way to find a place with us.


Sat

28

Nov

2020

Questions about phosphate sensors

In this article we have collected together some frequently asked questions regarding ZP's phosphate sensor.

 

 

 

1. Are your phosphate sensors intended for  agricultural or environmental applications?

 

Yes, see the ZP Ag Tech button below.

 

2. What measurement method is used?

 

See the phosphate sensor button below.

 

 

3. What are the LOD and linear range of the sensor?

 

This is a function of the sensor, electronics and application.

 

4. Are there any measurement interferences  (solution pH, dissolved oxygen, other Ions, etc.)?

 

Yes and these are application specific.

 

5. Would you please send me technical specification for this sensor?

 

Please see the phosphate sensor button.

 

6. Do you have any measurement examples to share, in which data from your sensor are compared to data from classical measurement methods?

 

See the ZP Ag Tech button below.

 

7. What are the calibration requirements?

 

Depends on the final application.

 

 

8. What is a sensor's response time?

 

 

Please see ZP's phosphate sensor button below.


Thu

26

Nov

2020

Thank you to NPL

This week, ZP would like to say thank you to the UK's National Physical Laboratory (NPL) for their recent work as part of the Measurement for Recovery (M4R) programme, which gives UK business access to world-leading measurement.

 

As part of a bigger programme to understand the performance of ZP's biosensors, the NPL team characterized a number of ZP's biosensors and screen printed electrodes, including our carbon 303 screen printed electrodes.

 

We were delighted with the work, because everyone  benefits from having another independent team taking a look at a problem. The NPL work directly identified ways of improving the reproducibility of our ZP sensors.

 

The NPL team are great as they have state of the art equipment, facilities and techniques. Their independence means that they don't carry 'internal team think' and so  bring a fresh perspective on a problem.

 

NPL have capabilities that go beyond microscopy and profilometry, including specialist techniques of  interest to the electrochemistry community including: scanning electrochemical microscopy (SECM) and electrochemical impedance spectroscopy (EIS).

The SPE that was characterized by microscopy and profilometry was the ZP 303 carbon electrode.

 

In the adjacent images we have some images gathered for ZP by NPL.


Thu

26

Nov

2020

Designing a biosensor for protein detection using a screen printed electrode

On this page we lay out one strategy to functionalize a screen printed electrode towards sensing a protein.

 

Links relevant to the video are in the buttons below.


Wed

25

Nov

2020

Calculating the cost of a first screen printing run

This page is designed to help you calculate the price for a first custom screen printing run at Zimmer and Peacock.

 

When you first have a batch of screen printed electrodes manufactured you have the non-recurring engineering charge (NRC).

 

The NRC is the one off costs of making the screens so we can print your electrodes, and the cost of the engineers to convert your designs into screens.

 

After the NRC is the cost of making the electrodes themselves. Please watch the video where we explain how to calculate the cost of a first run of screen printed electrodes at ZP.

 

Below we have six  buttons:

 

1) The cost of screens

2) The cost of engineering time

3) The cost to print on PET

4) The cost to print on ceramic

5) Our standard value electrode format

6) Our standard hyper value electrode format

Zimmer and Peacock offers free eLearning Modules relating to electrochemistry, screen printed electrodes and biosensing on the ZP Academy, click below.


Mon

23

Nov

2020

Raw material purification

This week our facility in Norway received  new lab equipment to support our lab engineers in their research and development. 

 

At ZP we have to make repeatable biosensors to exacting standards, and so we can't just use the starting materials as received, therefore we have added a rotary evaporator to the lab took kit to help with: extraction, purification and distillation.

 

 

Mon

23

Nov

2020

Parallel electrochemical processing

At Zimmer and Peacock we work with 12 channel Ana Pot and test jig to maximize our throughput.

 

Our test jigs are developed in house by our engineers to ensure that we can be as efficient as possible.

 

If you want to maximize your efficiency please contact ZP.


Mon

23

Nov

2020

Shipping biosensors this week

Zimmer and Peacock is the leading contract developer of electrochemical biosensors.

 

On our website you will find a wide range of biosensors for example glucose, lactate and potassium. If their is anything you can't find please do not hesitate to contact us.

 


Thu

19

Nov

2020

Electropolymerization and the formation of MIPS

In this video we discuss MIPs and their formation by electropolymerization.


Sun

15

Nov

2020

Designing an electrochemical sensor for protein detection

Here are some notes on how to design a system for the electrochemical measurement of proteins.

 

 

1. Which electrode materials  are useful for the measurement of proteins?

 

 

2. What  dimensions and geometry of the electrodes will make it suitable to the detection of proteins?

 

 

3. How to increase the sensitivity of the device towards the protein of interest?

 

 

4. How to minimize the interference from other proteins?

 

 

5. How to minimize non-specific binding and film formation that would otherwise confound the sensor?


Tue

10

Nov

2020

ZP welcome new members

At Zimmer and Peacock we are a constantly growing and on the look out for new team members to join us. This week we have had training and a walk through of our facility in Norway for our new members.

 

If you are interested in becoming a team member of our fantastic team, or looking for the right product for your research please don't hesitate to contact us. 

 

 

Sun

08

Nov

2020

Questions regarding screen printed pH sensors

At ZP we try to support the development and startup community so here are the answers to some commonly asked questions.

 

 

1. Is the ZP screen printed pH sensor single use or can it be re-used? Please comment on the the shelf life/operational  life of the sensor?

 

2. What is the pH range of the ZP screen printed pH sensor?
 
3. What is the necessary power  for using the sensor?
  
4. What is the measurement time of the pH sensor?
 
5.The pH sensor is potentiometric, how should I connect to it?
 
6. Does ZP recommend a  connector  to connect the sensor to a PCB?

 


IMPORTANT - If you are considering buying the ZP screen printed pH sensors please also purchase the ZP pH test solutions, this will mean ZP can properly support you especially when it comes to troubleshooting.

For those wishing to understand biosensors, including glucose and pH sensors in greater detail please click the link and watch our webinar 'Introduction to Electrochemical Biosensors and Demonstration.


Tue

03

Nov

2020

Accessories for 12 channel biosensor testing

At ZP we are passionate about developing tools and accessories for biosensors. We understand that you can't develop and test sensors one at a time, and so we develop the necessary tools to test 12 sensors at  a time, so that you can build up the statistical confidence in your technology. 

 


Mon

02

Nov

2020

Pros and Cons of screen printed electrodes

We were asked a very interesting question today at ZP to list the pros and cons of screen printed electrodes. The questions was '...what are the positives and negatives of screen printed electrodes when used for amperometric sensing...'

 

This was an interesting question so we answered it below:


Pros

  • Screen printed electrodes can be low cost once a lot of engineering efforts has been  been invested into them see Hyper Value and Value Sensor.

Cons

  • The perceived low cost of screen printed electrodes means that the quality of electrodes in the R and D community is in fact not that high.

  • There are companies that can print electrodes.
  • Many screen printing companies are not able to electrochemical test screen printed electrodes.

  • The quality of screen printed electrodes can be high.
  • Quality can be variable both from screen printed electrode to electrode and batch to batch variation, especially those offered to the R and D community

  • Applicable to amperometric and potentiometric sensors
  • Applicable to amperometric and potentiometric sensors, but if the manufacturing is variable it will effect the sensors raw signal, please see video.


Fri

30

Oct

2020

Questions regarding glucose sensors

We had some questions regarding glucose sensors from ZP, which are summarized here ...

 

Question 1 - What is the lifespan of this sensor?

 

Answer 1 - The answer to this question depends on whether you are referring to shelf-life or operational life.

We are linking to our main glucose sensor page below as it includes the datasheet which contains a lot of information and also on the page we have data showing the sensor in continuous operation for 48 hours.

 


Question 2 - Do I need to follow any maintenance or safety protocols while using this sensor or after the sensor usage?

 

Answer 2 - The sensors are intended to be used in a laboratory setting so good laboratory practice (GLP) should be followed, and personal protective equipment (PPE) as prescribed by your laboratory safety officer should be worn in your lab. Viewing the videos above should help. In addition there is  a comment regarding safety in the data sheet available on the main glucose sensor page. The sensors can be rinsed after use for storage, please see the button below.


Question 3 - Please tell me some analytical data regarding the sensor:

  • Linearity interval
  • LoD
  • LoQ
  • Operation stability

Answer 3


Wed

14

Oct

2020

ZP pH Sensors and Sensit Smart from PalmSens

On this page we discuss the use of ZP pH Sensors with the PalmSens Sensit powered by Analog Devices.

pH Sensor Test Kit

 

10 x solid state pH sensors.

1 x volume of pH 10 solution..

1 x volume of pH 4 solution.

150,00 €
Add to Cart
  • Available
  • Generally ships within 2-4 weeks

In the video below ZP shows how the Sensit Smart  from PalmSens and Powered by Analog Devices can be use to monitor pH.


Mon

05

Oct

2020

Chemical and biochemical sensors for condition monitoring

Condition monitoring is intended to extend the life time and up time of equipment, including machines, by continuously monitoring their condition, such as vibration and temperature, and using the data to see as a machine is moving away from its normal state (baseline data) and showing signs/signals of a developing fault. This process of monitoring is a major component of predictive maintenance. Parameters that are currently used to monitor the condition of machinery  includes: temperature, vibration and current/voltage through a model based voltage and current systems (MVBI systems). 

The sensors for temperature and vibration tracking have been available for decades, but at ZP we see a that the sensors for monitoring the chemical state of the machine system are not so readily available or are not developed.

 

At Zimmer and Peacock we are interested in sensors that can measure the chemical condition of a machine, including parameters such as corrosion and the condition of the lubricants.

 

At ZP we are interested in exploring with clients condition monitoring using our standard sensors including our conductivity sensors for lubricant and fuel condition monitoring.


Wed

30

Sep

2020

ZP Glucose Sensors and Sensit Smart from PalmSens

On this page we discuss the use of ZP Glucose Sensors with the PalmSens Sensit powered by Analog Devices.

Glucose Sensor Test Kit

10 x generation one glucose sensors.

1 x volume of 20 mM glucose solution.

1 x volume of 0 mM glucose solution.

150,00 €
Add to Cart
  • Available
  • Generally ships within 2-4 weeks

Each kit comes with a complementary coupon code allowing you to access the ZP glucose sensor training module for free at the ZP Academy.


Click the button to source the Sensit potentiostat


In the video below ZP shows how the Sensit Smart  from PalmSens and Powered by Analog Devices can be use to monitor the glucose/sugar in Coca-Cola.

Below ZP shows how the Sensit Smart  from PalmSens and Powered by Analog Devices can be used in conjunction with the ZP glucose sensor kit to develop glucose and potentially other biosensing applications.


In the video we do a show and tell on what is in the ZP Glucose Sensor Kit: 10 glucose sensors and two test solutions.

In the video below we give an technical description of the generation one glucose sensor.


Fri

04

Sep

2020

Register for our upcoming webinar

ZP has the largest range of off-the-shelf solutions for people intending to develop wearable and transdermal biosensors

 

As part of our support of industrial and academic developers we will be hosting another webinar including a live demo of wearable tech; the topic for this latest webinar will be ‘Introduction to Wearable Biosensors and Transdermal Biosensor’.

 

Please register for the webinar below.


Sun

30

Aug

2020

Crossing two chasms to get to the sensor and biosensor market

At ZP we are passionate about translating ideas around sensing into products. Our focus is biosensors and sensors and so this presentation focuses on difficulties with getting ideas to the market. This presentation is based on original ideas of Geoffrey Moore in his book 'Crossing the Chasm'.

Click the image to find this book online.


Thu

27

Aug

2020

Halal Biosensors

This week we had a very interesting webinar for our ZP Developer Zone Members, and the subject was Halal Biosensors/Sensors. We discussed alcohol sensors and DNA sensors for pork adulteration/contamination. In the adjacent video we discuss the development of Halal Sensors.


Mon

24

Aug

2020

How to detect APIs using electrochemistry and screen printed electrodes

In this video we discuss how to detect a pharmaceutical drug/API using electrochemical techniques specifically we recommend using a carbon electrode.

 

Links to pages we use in the video are below.


Mon

24

Aug

2020

Sensors and biosensors machine learning implementation life cycle

ZP is accelerating our collaborators to market through a combination of off the shelf biosensor products, electronics combined with customization development and manufacturing services, all focused around our core competency of electrochemical sensing and  biosensing.

 

Two of the tactics we deploy at ZP is to develop the best sensors we can, but to also apply the best data codes and models to the raw data. To this aim ZP is a leader in the application of machine learning to sensor and biosensor product development.

 

In the adjacent image we show the Machine Learning Implementation Life Cycle that we apply into our clients product development.



Mon

24

Aug

2020

ZP @Sensors in Medicine 2020

ZP is speaking on Thursday 22 October at the Sensors in Medicine 2020, where we will be talking in the wearables and implantable sensors session.

 

Click the buttons below to find out more.


Mon

20

Jul

2020

SPE conductivity sensors

At ZP we are a world leader in the manufacture of screen printed electrodes (SPE). In this data we show how our SPEs can be used as conductivity sensors, in the data we also compare against a traditional conductivity probe.

 

In the buttons below we show links to the electrodes used in this study.



Thu

16

Jul

2020

ZP - Manufacturing data for solid state pH sensors

At ZP we manufacture our pH solid state pH  within our ISO13485 quality management system, applying our standard operating procedures/work instructions and our acceptance criteria. To characterize our solid state pH sensors manufacturing ZP has carried out a multi-step investigation.

 

 

STEP ONE - Manufacturing phase

ZP performed a manufacturing step where we manufactured three batches of 108 pH sensors on three different days.

 

 

STEP TWO - Testing phase

Next ZP functionally tested five random sensors from each batch. The solid state pH sensors were tested with pH solutions between pH 2 to pH 10, please see adjacent raw data.   As a side note ZP is unusual in that we have both high-throughput manufacturing capability and high-throughput testing capability, click here. This functional test capability was used in this study.

 

STEP THREE - Data processing phase

Having gathered the data ZP then used our data processing group to apply a mathematical baseline correction to the data, where we mathematically moved all of the data to a baseline of 0 V at the initial pH 2, please see the adjacent data.

This baseline correction is equivalent to a one point calibration. It should be noted that an even more accurate way of calibrating pH sensors is of course to perform a two point calibration, but it was unnecessary for this study. Click here to see our data group.

 

STEP FOUR - Data analysis phase

Having processed the data ZP next analysed the data.

 

ZP has a very sophisticated set of technologies and workflows in-house for the conversion of data into actionable information, click here to find out more.

 

STEP FIVE -  Reporting results phase

The result of our testing was that across all three batches and having performed a single baseline correction 75 % of all the sensors within the population of 324 pH sensors gave  a measured result that was within 85 % of the actual result, i.e. for a pH of 7, the overwhelming majority of the pH sensors from the three batches would read a value in the range 5.95 to 8.05.

STEP TWO

STEP THREE

STEP FOUR



Sun

12

Jul

2020

Commercializing a sensor for antibiotic detection

We recently had a an enquiry on how to commercialise a biosensor for antibiotic detection.

 

We have paraphrased the enquiry below, on this page we give a quick response.

 

... how can we manufacture electrochemical biosensors for antibiotics detection in water bodies , specially how can we make them low cost

 

1) what will be the manufacturing process 

 

2) how much time it will take to manufacture them

 

3) what resources are required for manufacturing,... like plant building, land or amount of space required and people required for manufacturing processes

 

4) what can be its estimated shelf life 

 

5) how can we design it 

 

 


Wed

24

Jun

2020

The cost to bring a medical diagnostic onto the market

At ZP we perform contract development and manufacturing of electrochemical biosensors, one of the questions we are regularly  asked is 'what does it cost to bring  medical diagnostic onto the market?'

 

In answering that questions we can use our industrial experience, and we can use the opinions and data from other world leaders in this field. In this article we reference  excellent article on the Diaceutics website which can be found here.

 

 

 

 

ARTICLE FROM DIACEUTICS

 

The original article is here - click here.

 

In the adjacent table we have read and understood the information from Diaceutics and added our own take on their numbers.

 

You can see that Diaceutics gave a value in the range $20 M to $100 M.

 


CONCLUSION

 

At ZP we are always excited to work with clients who are ambitious and are driving to the market, and of course we want to support people on this road. We hope that these notes will help people in their buisness planning and their buisness models.

 

If you have questions regarding ZP's contract development and manufacturing services for IVD, please don't hesitate to contact us.  


Mon

01

Jun

2020

Sensors for water quality

Zimmer and Peacock has the worlds widest range of electrochemical sensors and biosensors on the market. Our customers, clients and collaborators  can engage with our technology, either by:

 

1) Partnering with us through one of our off the shelf solutions.

 

2) Contracting with us to develop and manufacture a bespoke sensor.

 

Below we link to the sensors and electronics appropriate to developers of water quality monitoring applications.

 

The sensors in the ZP biosensor range applicable in water quality applications include: conductivity/salinity, sodium, potassium, phosphate, ammonium, calcium, pH, chloride and oxygen.  If you can't see the sensor you are looking for please don't hesitate to contact us.





Fri

22

May

2020

Searching for potential CEOs

The ZP Group is under going massive growth, but we know that the foundation of growth is having  excellent clients and an excellent team, where our team is  delivering world leading services and products to our clients.  

 

For the ZP Group growth to be sustainable we fully appreciate that we have to increase our team and our network and so we are reaching out through  our primary, secondary and tertiary connections for individuals who can participate in leading our spin out ventures. 

 

We have a number of internal and external programs within the ZP group that are maturing and will require substantial funding, but ZP understands that funding needs to be linked to an effective CEO; that is why ZP is reaching out through our network for people with the intelligence, drive and organisational skills to be part of seeding and running new ventures.

 

The ZP Group is focused on electrochemical biosensors and the real world applications of these sensors, so please assume that you would be coming into a rich ecosystem of engineering and scientists centered around the deployment of sensor and the delivery of sensing data into business and/or consumer actionable information.

 

At ZP we know that  the conversion of world  beating capability into market ready products and services will take great leadership, energy and focus from individual who can share a vision.

 

If you want to start exploring the next step in your life, with a view to seeding and running a business, please don’t hesitate to contact Even or Martin through linked in.


Please click click below to contact Even on LinkedIn

Please click below to contact Martin on LinkedIn


Sat

16

May

2020

Hydrogen peroxide sensors for vaporized hydrogen peroxide applications

Vaporized hydrogen peroxide (VHP)/hydrogen peroxide vapor (HPV) is used as a broad spectrum anti-microbial, and is used to decontaminate small objects to entire hospital wards.   The use of VHP has risen to prominence during COVID-19 pandemic. It is considered a means by which to sterilize the Corona virus.

 

The hydrogen peroxide is passed onto the sample or into the ambient environment in the form of a vapor by a VHP generator.  The issue is that many of the hydrogen peroxide generators on the market generate vapor in the range 140 ppm to 1400 ppm during their decontamination cycle, and this needs to be cleared before an area can be re-entered. A VHP concentration of 75 ppm or more is considered immediately dangerous to human health and life.  An area is considered safe to enter once the VHP is < 1 ppm.

 

Zimmer and Peacock provides a VHP hydrogen peroxide sensor, intended to be used by manufacturers in their VHP applications and products..

Hydrogen Peroxide Sensors - VHP

Hydrogen Peroxide sensors for VHP  applications where the sensor is disposable or where continuous measurement is required.

195,00 €
Add to Cart
  • 1 kg
  • Available
  • Generally ships within 2-4 weeks
VHP - ZP hydrogen peroxide sensor datasheet
ZP - H2O2 sensor.pdf
Adobe Acrobat Document 123.1 KB

Fri

15

May

2020

ZP Cell

The ZP Group is looking to grow our geographical network and reach in part through our ZP Cell Network.

 

Our ZP Cell Network is looking for talented scientists and engineers, with a background and/or an interest in electrochemical biosensors who want to collaborate with the ZP Group.

 

ZP has a global customer base and so we are looking for truly entrepreneurial scientists or engineers geographically distributed, who can engage with our ZP team and support our clients and programs in their region. 

 

 

If you are interested to be part of our ZP Cell Network, please contact us.


Fri

08

May

2020

ZP - Self Assembled Monolayer Biosensors Developers' Resource Page

Welcome to ZP's resource page for developer of biosensors who are looking to develop a biosensor on a gold electrode, using self assembled monolayers. 

 

The principles that summarize the content of this page includes, the electrochemical detection of biologically relevant molecules through the specific binding of an analytes to a surface, where the detection technique is electrochemical. The techniques we promote include: electrochemical  impedance spectroscope (EIS), differential pulse voltammetry (DPV), square wave voltammetry (SWV), chronoamperometry (CA), etc.


In the buttons below we have provided short cuts to material and information on ZP's website that we see as relevant. We also include our contact button, please do contact us as a thirty minute online chat can save you months of effort and get you on the right path to success and commercialization.

How to form a SAM layer.

Recommended potentiostats.

Obtaining a signal.

Contact us.

The actual experiment  can be quite simple as shown in this illustrative video.


Tue

21

Apr

2020

Questions to ZP regarding biosensors

ZP had a series of questions regarding our sensors, which are listed below so we decided to answer them in a video, see the questions here.

 

 glucose,

1. Resolution:

2. limit of detection:5mM

3. redox potentials:

4. Interval concentration: 0-20mM

5. etc

 

 lactate, 

1. Resolution:

2. limit of detection: 1 mM

3. redox potentials:

4. Interval concentration: 0-4 mM

5. etc

 

 

sodium and 

 

1. Resolution:

2. limit of detection: 40 mM

3. redox potentials:

4. Interval concentration: 0 - 360 mM

5. Sensitivity:  0.02 Log (C)/mV

6. etc:

 

 

potassium

1. Resolution:

2. limit of detection: 2.7 mM

3. redox potentials:

4. Interval concentration: 0-7 mM

5. etc

Click below to see our range of sensors.

If you have any questions please contact ZP.

 

 


Wed

15

Apr

2020

Direct SARS-CoV-2 Detection - COVID-19

At  ZP and Aliksir we are manufacturing our first batch of electrochemical biosensors for the direct detection of SARS-CoV-2 as our contribution towards the fight against COVID-19.

 

Our rapid development of this sensor was made possible because ZP's  team has now been together for over six years and delivered on over fourty biosensor development  and manufacturing programmes. The ZP team spans from biology through electrochemistry and electromechanical  to quality engineering.

 

For this sensor to truly be impactful we are looking for companies and entrepreneurs who have the vision and resources to take this all the way  to market with us.

 

Please don't hesitate to contact us if you have a vision to get this thing beat.


Mon

13

Apr

2020

Electrochemical RT-PCR detection for COVID-19

Welcome to our discussion on the electrochemical detection of COVID-19 using reverse transcription polymerase chain reaction (PCR).

 

Though PCR is entering the widely used lexicon it is not always understood; a simple definition of PCR is a method by which DNA can be amplified so that it can subsequently detected or measured. The term amplification in this context means that the amount of DNA is increased (multiplied) by the polymerase chain reaction.

 

There is a hyphenated version of PCR, which is relevant when discussing COVID-19, this is real time PCR, also known as quantitative PCR (qPCR). In qPCR it is possible to measure the amount DNA as a function of time/cycles.  The time it takes for DNA to be detected is proportional to the amount of target DNA in the original sample and so the real-time PCR/qPCR can be a quantitative. 

 

Of course, COVID-19 a virus and hence has RNA as opposed to DNA. Therefore, when you look at the tests on the market for the detection of an active COVID-19 infection many are best described as RT-PCR, where the RT stands for reverse transcriptase. The sequence of events in aCOVID-19 RT-PCR is that the COVID-19 RNA first undergoes transcription from RNA to DNA, and subsequently the DNA is amplified (multiplied) and in real time the amplification of the DNA is measured.

 

A flaw in RT-PCR detection of COVID-19 is that it often involves a fluorescent t dye, and it is the binding of this dye to the amplified DNA from the PCR, which is the source of the signal. The issue is that it is hard to make fluorescent base instruments low cost and portable. When you look at the list of commercial fluorescent-based RT-PCR instruments for COVID-19 the smallest are tabletop units, and none can be described as handheld and low cost.

 

What is required is a small handheld COVID-19 RT-PCR instrument with the same costs and size as a glucose meter.  In order to achieve this the detection science has to be transferred from fluorescence to electrochemistry. All handheld glucose meters on the market are based on the science of bio-electrochemistry, which allows them to be manufactured at relatively low prices.

 

To convert a fluorescence RT-PCR to an electrochemical RT-PCR is straightforward with a lot of examples in the literature, and a simple google search on ‘electrochemical RT-PCR’ will yield pages of academic hits.

 

At ZP we have a number of technologies available through our webstore to help those wishing to develop low cost RT-PCR COVID-19 tests using electrochemistry, please don’t hesitate to contact us.

 


Thu

09

Apr

2020

COVID-19 biosensor developers resource centre

There are concerns that the COVID-19 lateral flow antibody tests are not as clinically useful as first hoped, and that bench top PCR tests are not as scalable as the necessary for all the testing COVID-19  will demand.

 

This means that there is a need for quick and easy to use biosensors, which are as manufacturable  as glucose sensors.

 

Zimmer and Peacock's business model is to partner with companies and entrepreneurs to rapidly develop and commercialize biosensors, using materials and manufacturing techniques otherwise used in glucose strip manufacturing.

 

On this page we provide a series of links useful to any companies or individuals interested in developing and manufacturing a COVID-19 biosensor.

 

If you have any questions regarding the content of these pages please don't hesitate to contact us.


THE SENSOR

 

The classic way to functionalise an electrode towards a virus of interest is to immobilize an appropriate macro-molecule to the surface of an electrode. The function of the macro-molecules to give the electrode specificity towards COVID-19.

 

The technology commonly used to immobilize macro-molecules to electrodes is SAM (self-assembled mono-layer).

 

In the adjacent buttons we provide some information on anyone thinking of developing a COVID-19 biosensors using gold electrodes and SAM technology.

THE ASSAY

 

Zimmer and Peacock's philosophy for COVID-19 assay development is try and keep it simple. Therefore in the adjacent button we discuss a philosophy on how to design a viral assay, whilst keeping it simple.

THE ELECTRONICS

Zimmer and Peacock has a wide range of electronics for COVID-19 biosensor developers, from their R and D phase through to their product launch.

 

We have included some useful buttons here, but we would highlight the FoodSense platform, as this platform has a readiness level that is useful within the timescale of the current COVID-19 crisis.

CONTRACT DEVELOPMENT AND MANUFACTURING SERVICES

Zimmer and Peacock is a dynamic team of IVD developers and manufacturers, if you want to discuss your development and manufacturing needs for a COVID-19 assay please don't hesitate to contact us.


Thu

09

Apr

2020

ZP technologies for the analysis of wine

At Zimmer and Peacock we are experts in developing and manufacturing electrochemical biosensors. One of the  strength of the company is our broad understanding of applications including the analysis of wines.

 

Many of the aromatic molecules within wine including the polyphenols, tannins, anthocyanins, flavonoids are detectable by our technology. At the same time our sulfite in wine  and pH sensing technology can augment the characterization of wine.

 

ZP can implement our core technology either for discrete single point testing or in a continuous analysis mode where the wine is monitored as a function of time.

 

 

We have put some buttons below to help people explore our wine centric expertise and technologies, including  a link to our AI technology. We see wine and  AI being a powerful combination  due to the complex chemical matrix of wine.

 



Thu

02

Apr

2020

What is the selectivity of ion-selective electrodes (ISE)?

Selectivity of ISE

 

When answering the question 'what is the selectivity of an ISE?' it is useful to use the selectivity coefficient.

 

The higher the selectivity coefficient value of, k, the more selective the ISE is towards X relative to A.

 

Sodium ISE

If we use the example of the ZP sodium ISE, then we have the following selectivity coefficients:

 

  • Na,K 0.6
  • Na,NH4+ 0.2
  • Na,Ca2+ 0.02
  • Na,Mg2+ 0.03

These selectivities   can be interpreted by understanding the ratios of these ions within the application, e.g. if the Na/K ratio is > 20 then there is no significant interference of potassium ions with the ZP sodium sensor.

 

Similarly if the Na/NH4+ ratio >10, then again there is no significant interference from ammonium and finally if the Na/Mg or Ca ratio is >1 then there is no significant interference of these ions to the ZP sodium sensor.

 

Whether the ZP sodium ISE is specific enough relative to ions such as potassium  depends on the application of interest. If we consider sea water or blood then the sodium to potassium ratio is intrinsically high.  In the case of blood the sodium concentration is approximate 135 mM whilst the potassium concentration is approximately 4 mM , therefore the Na/K ratio  = 34, so the ZP sodium ISE sensors is not effected by potassium within this application.

 

Potassium ISE

 

The ZP potassium ISE uses a very selective ionophore, and so the selectivity coefficient of the ZP potassium sensors means an excellent selectivity towards potassium in the prescence of other ions, as reflected in the selectivity coefficients:

 

  • k K,Na 0.0004
  • k K,NH4+ 0.01
  • K,Ca2+ 0.003
  • K,Mg2+ 0.0001

 

 

 

Zimmer and Peacock has a large range of ISE among withinour sensors catalog, please click the button below to search our range of biosensors including ISE.


Tue

31

Mar

2020

ZP Lab - Sensor, Biosensor and IVD Incubator

ZP AS launches an onsite and online  biosensor incubator.

 

ZP AS has launched the world’s first biosensor and IVD incubator both onsite and online. We are living in a IoT revolution where everything will be connected to the Cloud/internet and where data will be continuously streamed and translated into actionable information in real time by AI.

The issue is that when you survey the world’s sensor landscape you find that whilst there are thousands of condition sensors such as temperature, pressure, locations, movement sensors etc there is a distinct lack of chemical and biochemical sensors. The irony is that most of the data streams that are commercially interesting are the biological, biochemical and chemical data, but the necessary sensors such as: glucose, lactate, oxygen, hydrogen peroxide, pH, nitrate, phosphate, potassium, sodium calcium, alcohol, redox, etc were not commercially available.  At ZP we have many of the biological, biochemical and chemical sensors that would otherwise be missing from the commercial landscape.  Our business model has always been to accelerate our customers and clients to market and so we have these sensors on the shelf so that companies and entrepreneurs can quickly test an idea or a concept and not be inhibited by the lack of a sensor.

Our experience at ZP is that companies, academics and entrepreneurs will buy and try one of our off the shelf sensors, gather some proof-of-principle data and then move forward with us to develop a sensor that are more tailored towards their idea, market and application.

 

At ZP we are by default a collaborative business and we know that we will move faster and more efficiently with partnerships and so we are delighted to announce our efforts to start rolling out the ZP Incubator. Our incubator is intended to help entrepreneurs, companies and start-ups to get going faster and more efficiently on their sensor ideas.

 

To apply to join the ZP Incubator you do need to meet a minimum of three criteria:

 

• CRITERIA ONE – You must an idea or a technology that involves an electrochemical sensor.

• CRITERIA TWO – You must have an idea that has commercial merit with a path to market.

• CRITERIA THREE – You must have a source of funding to get you some way to the market.

Please do note that meeting these three criteria does not guarantee an acceptance to join the incubator, but please do try.

Our first onsite incubator is located next to our ZP AS HQ in Norway. If you join our hub you will have access to a team, equipment, technology and manufacturing capability able to take you to market

 

If you would like to contact ZP regarding our ZP Incubator, please contact us.

Sun

29

Mar

2020

The cyclic voltammetry of ferricyanide/ferrocyanide

In this video we show you how to run a first experiment for ferri/ferrocyanide on a ZP potentiostat and screen printed electrode.

 

All the equipment used in the video can be found here.


Sun

29

Mar

2020

PhD - Molecular Dynamics Simulations of Graphene-Protein interactions for Biomedical Diagnostic Sensors

Applications are invited for a three-year MPhil/PhD studentship. The studentship will start on 1 st October 2020.

Project Description

Fundamental understanding of protein dynamics, energy landscape and conformational changes, is central to deeper insights into a protein’s specific biochemical functions (such as allosteric signalling, enzyme catalysis etc.). This could aid in drug discovery, novel protein engineering and distinguishing between normal and pathogenic conformational changes for disease diagnostics applications. In this project we aim to investigate a novel approach for the detection of protein dynamics and interactions on the surface of Graphene (and related two-dimensional materials, G2DM) through direct comparison of Molecular Dynamics Simulations (MDS) with experimental results obtained from our G2DM based sensors developed at the University of Plymouth in collaboration with the University of Cambridge.

For the MDS we will employ the Kohn–Sham (KS) formalism of the density functional theory approach to perform the in-silicio study of the graphene-protein system. The KS approach has proven to be one of the most efficient and reliable first-principles methods for investigating material properties and processes that exhibit quantum mechanical behaviour. The pioneering

nature of this research will enable the student to use BigDFT massively parallel electronic structure code to simulate the graphene-protein sensor, based on the High Performance Computing Cluster at the University of Plymouth, as well as making comparisons with cutting edge experimental measurements. Accurate comparisons between MDS and experimental

results has the potential to lead to a breakthrough in our understanding of protein dynamics and conformational states, thus opening a plethora of applications in diagnostics, prognostics and therapeutics particularly for Alzheimer’s, cancer and cardiovascular diseases. 

CLICK THIS DOCUMENT TO FIND OUT MORE

portsmouth PhD
Adobe Acrobat Document 289.6 KB

Thu

19

Mar

2020

Testing and validating a COVID-19 Diagnostics

At Zimmer and Peacock we have a can do attitude and so during this COVID-19 pandemic we are busy validating biosensor solutions to help protect public health.

 

We do understand that the best solution is a vaccine but until that is readily available ZP will do it's part and continue to validate the COVID-19 test.


Wed

05

Feb

2020

USN - Introduction to Biosensors

Thank you for attending our talk today at USN, please download the presentation here.

 

If you are interested in having a collaboration with ZP please contact us.

 

Please download the presentation here.

 

Zimmer and Peacock Biosensor Workshop_US
Adobe Acrobat Document 7.1 MB

Thu

14

Nov

2019

Setting up a wearable sensor

Recently one of our engineers walked a client through the set up of their ecFLEX - a wearable biosensor platform.

 

In this note we report the guidance that the engineer gave.

 

STEP ONE - Connect the ecFLEX to the sensor.

 

STEP TWO -  Connect the battery to the ecflex using the crocodile clips (the black crocodile clip is isolated underneath to avoid shorting) and keep the black crocodile clip on the side near the components.

 

STEP THREE- Once the ecFLEX is powered download the readout software.


STEP FOUR - Once the readout software is up and running, you have to press scan and find your ecflex listed (Tx should be higher than -127 dBm).

 

 


STEP FIVE - You connect to your device by double clicking the name of your device and waiting for the settings to upload (everything will be automatic, you do not need to change anything in the software settings). Once the device is connected, the Tx will show -127 dBm so do not worry:


Lastly one of our engineers put out a super useful video on YouTube, please watch to lean more.


Thu

31

Oct

2019

Vaporized hydrogen peroxide detector

ZP's hydrogen peroxide sensor for vaporized hydrogen peroxide detection  is a handheld mobile system that can be deployed to measure the hydrogen peroxide vapour in an atmosphere.

 

ZP's VHP meter can be deployed during decontamination to check  the vapour hydrogen peroxide levels, and post decontamination to ensure that levels are safe for  operators. 

 

ZP's VHP meter is unique as the world's only handheld portable VMP meter. Further it is the only meter to use enzyme technology to detect hydrogen peroxide so is inherently the most specific hydrogen peroxide meter on the market.

 

The ZP cartridge system means that the hydrogen peroxide sensor can easily be replaced in the field and avoids  having to send sensors back to the factory for calibration.


Fri

18

Oct

2019

How to connect to a microneedle array?

At Zimmer and Peacock we appreciate the importance of having a good connection between your microneedle array and your electronics,so that you can have the best possible signal.

 


Sun

29

Sep

2019

Ion-Selective Electrodes (ISE) and Ion-selective Field Effect Transistors (ISFETS)

So many of the biosensors from Zimmer and Peacock fall  into the category of Ion- Selective Electrodes (ISE), at the time of writing the list includes: pH, potassium, sodium, chloride, calcium, nitrate, ammonium and phosphate.

 

Some of the these ISE sensors can be seen in action by clicking  the button below.

See our range of sensors, including  our ISE sensors here.


At Zimmer and Peacock we have a lot of characterization data, some of which is on our website, but if you can't find what you are looking for please contact us.


One of the technical advantages of the ZP ISE is that they can come with a chloride resilient electrode, so that the sensors can be used in applications where the chloride ei sunnow or uncontrolled.


Sun

29

Sep

2019

Low cost sensors for IoT and scientific instrumentation

When people talk about multiple sensor system and the IoT they are describing multiple sensors monitoring a system be it a body of water, a manufacturing process etc.

Traditional chemical sensors, such as the glass barrel pH sensor, do not translate well into multiple  sensor networks. This is because traditional sensors were originally designed for lab applications, where low cost and robustness were not considerations alongside functionality and accuracy.

At ZP we know that when you combine electrochemical sensing technology with low cost manufacturing principles you are able to manufacture a sensor with the right cost and functionality. 

 

 

 

 

 

 


At ZP we have an extensive range of sensors, where the fundamental technology and manufacturing principles makes them perfect for those working on sensor network products.


Wed

24

Jul

2019

Resources for the Electrochemical Sciences

At Zimmer and Peacock we are focused on electrochemistry, both from the research perspective but also from the commercialisation perspective.

 

Below we have linked to resources on our website regarding electrochemistry be it:

 

1) Energy Conversion and Storage - Fuel Cells, Bio-fuel cells, Batteries and Flow Batteries, Electro-catalysis and Photo-electrocatalysis.

 

2) Photo-electrochemistry - Solar Cells, Perovskite, and alternative Solar Cells.

 

3) Corrosion - Marine Corrosion, Coatings, Paints, Polymers.

 

Please click the buttons below to access extra resources or contact us to ask specific questions


Mon

20

May

2019

Heavy Metal Detection

One of the keywords that describes us at Zimmer and Peacock is electrochemistry and so we approach the development of sensors and sensing from an electrochemist's perspective. That is why when people ask us can we provide or develop a sensors for heavy metal detection the answer is YES, but most importantly we also approach the answer form the perspective than for an electrochemist heavy metal detection is an 'easy' and well understood technology.

 

In the adjacent image we show the wave form and expected raw data from analysing a solution of heavy metals.

 

The technique that we recommend is anodic stripping which is an analytical technique that involves preconcentration of a metal onto an electrode surface followed by selective oxidation of each metal during an anodic potential sweep. 

Stripping analysis has the following properties: 

  1. Sensitive and reproducible (RSD<5%) method for trace metal ion analysis in aqueous media.
  2. Concentration limits of detection for many metals are in the low ppb to high ppt range (S/N=3) and this compares favourably with AAS or ICP analysis.
  3. Field deployable instrumentation that is inexpensive, approximately 12-15 metal ions can be analysed for by this method. 

The method is quantitative a the stripping peak currents and peak widths are a function of the metal concentration in solution.


In the buttons below we have linked to the instrument and electrodes for starting your development, if you have any questions regarding Zimmer and Peacock please don't hesitate to contact us.

 

 

Fri

03

May

2019

pH sensor stability and calibrating a pH sensor

At ZP we are often asked what is the accuracy of the ZP electrochemical sensors and biosensors, but the answer to the question is 'how do you intend to use them?'. The accuracy of an electrochemical biosensor is a function of the sensor, your sample and your system in which you place the sensor.

 

The second question  is how will your sensor work in my fluid, and these can range from: urine, blood, plasma, serum, saliva, breath, foods, beverages etc, a sub-question to this question is what will the drift be like. Again the answer to this questions is as above, and the way the sensor will respond to your sample depends on your sample and the degree of drift with time depends on the sensor, your sample and your system. In this note we do give a calibration routine that will allow you to compensate for drift and keep the overall system accurate.

 

Though this note is written with the ZP pH sensors specifically in mind the equations/similar equations  and calibration strategies are applicable to many of our other potentiometric sensors including: nitrate, ammonium, phosphate, sodium, potassium, chloride  and calcium.  At the same time similar equations and calibration routines are applicable to our amperometric sensors: glucose, oxygen, lactate and nitric oxide sensors.

 

 

As stated above this note is specifically focused on pH sensors, and the problem that we are trying to solve is drift in pH sensors which are expected to be in continuous use for hours/days.

 

We have illustrated the problem in the adjacent figure, where a pH sensor is in a constant pH solution at a constant temperature and the signal is stable/perfect. The reality is that the signal can/does drift. In this note we explain the maths behind the senors and where the source of drift could be coming from and then calibration routines to counter the drift.


In the adjacent image we have started with an equation based on the Nernst Equation, Equation 1, and rearranged it to Equation 3. If we look at Equation 2 it says that the raw signal will be constant when pH, temperature, constant 1 constant 2 and constant 3 are all stable. What Equation 3 indicates is that to remove the influence of temperature from the signal either the analysis should be done at a controlled temperature or the sample temperature should be monitored. 

 

The reality with pH sensors is that constant 1, constant 2 and constant 3 are not stable, and so if you have wondered why there is always/often bottles of pH calibration solutions next to the lab pH meter it is because of the drifts in these constants; in the rest of the note we discuss re-calibration techniques.

 

 

 

 

 

 

 

ONE POINT CALIBRATION

 

If it is only the Constant 1 in Equation 3 that is drifting then a one point calibration is sufficient. What we mean by this is that a solution of known pH is placed in contact with the sensor and the Constant can be calculated from Equation 4. The now re-calculated constant can be put back into Equation 3 and the accuracy of the system improves and the drift in the raw signal will not be reflected in the displayed pH.  In the adjacent image we show raw data from a ZP pH sensor, the steps in the data reflect the changes in signal as the pH is changed from pH 2 to 9 and back again. It should be noted that the sigan is stable over 1600 seconds/30 minutes. We would therefore suggest that the ZP sensors are at least stable over 30 minutes and shouldn't require calibration in that time. Please note a one point calibration is most effective when measuring a sample that should be at a specific pH, for example pH 7.2. In this case one uses a calibration solution that is similar to the sample solution and is also buffered at pH 7.2

 

 

TWO POINT CALIBRATION

 

A one point calibration described above is fine if we assume that the drifting is due to the Constant 1 in Equation 2, but is due to the pH Sensitivity drifting  then we need to perform a two point calibration. In the embedded excel file opposite we have embedded the maths to do a two point calibration. To make the spreadsheet work, then the user/system needs to expose the sensor to a calibration solution at pH 4 and record the mV signal (the default in the spreadsheet is 150 mV), next the user/system needs to expose to pH 10 (the default in the spreadsheet is pH -60), from that the spreadsheet calculates the Constant 1 and the pH Sensitivity. These values can be placed back into Equation 4 and the overall system will then calculate the pH more accurately. Typical values used to calibrate a pH sensor are 4 and 10 but the best way to get an accurate calibration is to use calibration solutions whose pH values are reflective of the expected pH range of the solution.

 

 

HARDWARE SETUP FOR RECALIBRATION

In the adjacent image we show an example of a hardware setup that can be used for one point and two point calibration.

TEMPERATURE COMPENSATION

The topic we have not yet discussed in this note is temperature compensation, please note that this page is a live page and ZP are busy gathering the temperature characteristics of the pH sensor.


Mon

15

Apr

2019

Two important developments on the ZP sodium sensors

At ZP we are aware that we have 'too many' biosensors, and as the demands of our clients increase and as many approach the market then we have moved to improve the sensors. In this note we discuss that the sodium sensors have been improved in two important ways:

 

1) CHLORIDE RESILIENT - We now have a sodium sensor that is chloride resilient, what we meant by this is that the reference electrode does not change it's voltage as the chloride concentration changes.  In many blood, plasma and serum applications the chloride concentration is fairly fixed at around 150 mM and so the fact that the silver/silver chloride reference electrode is chloride sensitive doesn't matter, but in other fluids this is not the case. In the new sensor the reference electrode is  chloride resilient and so suitable for applications where chloride is variable or unknown

 

 


2) LONGER TERM STABILITY - In the adjacent image ZP has run two of its chloride resilient sodium sensors in 40 mM sodium solution for 64 hours. Both sensors kept within a 40 mV wide band. This would mean that the sensor was showing a change that was equivalent to going from 40mM to approximately 160 mM. Both sensors were on the same solution but were in fact run on separate instruments. This would make one think that something extrinsic to the sensor and the solutions was causing the solutions/sensior to change its apparent sodium concentration; an obvious parameter would be temperature. One would conclude that if we repeated the experiment but with temperature control then the apparent stability would be improved.

 

As we suspected that our data had been influenced by temperature we repeated the test but in a lab with a much better temperature control. The result was that after the initial setting time the signal was more stable so provides evidence that the sensor is temperature sensitive and so oen will either monitor or control the temperature when in use


Mon

15

Apr

2019

ZP Norway Workshop on Biosensor Development and Commercialization

Who should come?

Anyone who is interested in developing and commercialising sensors based on electrochemistry.

What will happen?

This will be a highly interactive course/workshop, people will be encouraged to interrupt and ask question as we go along, you will do real practicals in our labs, so it WILL NOT all be theoretical.

Workshop content?

Please click the button below to get a flavour of the course.

 

Price?

The workshop will be  750 Euros and does not include accomodation.

 

Accommodation?

Please click the link here to see the hotel in walking distance - link.

 

Location

The workshop will be held at our ZP - Norway site in Horten.

Time and Date

The workshop will be held on the 4 September 2019 from 10 AM to 5:30 PM.


Wed

06

Mar

2019

pH monitoring in bioreactors and cell culture

At ZP we are super interested in many  types of biosensors including pH sensor. At ZP we appreciate that pH sensors have not changed in 40 years, so at ZP we are leading the revolution in updating and upgrading pH sensors both for discreet and continuous  monitoring.

 

The technology at ZP offers pH sensors at a few cents per sensors when purchased and used in volume.

 

 

In this note we describe the continuous monitoring of the pH levels of the media within a bioreactor, specifically we have used E. coli DH5α which has been  cultured in lysogeny broth (LB) for 24-48 hours. During this time the sensor was

recording the potential/pH of the solution by OCP. The sensor was tested for pH sensitivity using the standard pH4, pH7 and pH10 reference solutions at 10 minute intervals both before and after the microbiological test to firstly ensure that the sensor was pH sensitive before the test began, and secondly to assess what impact (if any) the exposure to the

bacterial solution had upon the sensors pH sensitive properties.


Wed

20

Feb

2019

Choosing inks for screen printed electrodes

INTRODUCTION

At Zimmer and Peacock we are pragmatists, which means we will choose the best materials for the particular application.  When manufacturing a screen printed electrode the choice of ink can be critical or not depending on what the ink will be used for.  When it comes to sensors and  assays developed on screen printed

 

In this note we discuss a comparison between two carbon inks from two different suppliers. When choosing an ink there are generally two categories of properties that are that .are considered and one that is overlooked, these are: printability, electrical properties and electrochemical properties.

 

The printability/rheological properties of an ink and paste are of course in the datasheet of the vendors, and similarly the electrical properties of the ink appear on the datasheets. What is not so much discussed is the electrochemical properties of the ink.  Whether the electrochemical properties are important then depends on what kind of assay is being run, whether is is an impedance, amperometric, voltammetric or potentiometric assay.  There are no definitive rules, but one could argue that electrochemical properties are important when the assay is voltammetric in nature. If the assay is potentiometric for example then the electrochemical properties are less important.  We illustrate this within this article.


We tested two inks from two vendors which were both described as carbon inks: INKS A and INKS B. We were able to print both inks, and when measuring the resistance both had similar conductivity.  

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WAFER MAPPING

Once the inks were printed ZP used its wafer mapping technology to assess electrodes fabricated from A and B.


ELECTROCHEMICAL TESTING

Both inks were tested for their electrochemical behavior, and whilst Ink B gave reasonable peaks, ink A did not give the expected electrochemical behavior.


FUNCTIONAL TESTING

Having determined that the electrodes were electrochemically different we could clearly say that for a voltammetric assay ink B performed better than ink A. We then tested both as amperometric and potentiometric sensors. Following these tests we could argue that both ink A and ink B were able to be used in the amperometric and potentiometric inks.


WHY ARE THE INKS DIFFERENT

In the adjacent image we show the route cause of while both inks are conductive one is better for voltammetric assays; the root cause is the ratio of organic binders to metal/metalloid on the surface. Higher the ratio of organic binder to metal/metalloid then the higher the resistance and therefore the more distorted the voltammetry .


Sun

10

Feb

2019

ZP Wearables Munich

ZP knows that one of the futures for the garment and sportswear industry are wearable biosensors. All the easy parameters such as ECG, pulse, temperature have been measure, BUT at ZP we are tackling the hard parameters, including: lactate, glucose, hydration, pH, sodium, potassium in a wearable format.

 

Our mission at ZP is to accelerate the time it takes get smart wearable biosensors to market.

 

ZP is a super friendly company so please don't hesitate to contact us.


Sun

10

Feb

2019

Manufacturer of Screen Printed Electrodes

OVERVIEW

At Zimmer and Peacock we carry our contract development and manufacturing of electrodes, sensors and biosensors. ZP is different in that we understand and can perform the entire workflow from: printing to functionalizing, to addition of microfluidics to final calibration of batches.

 

In this article we expand upon this and describe some ways of getting to market quicker.


MANUFACTURING ELECTRODES 

The issue with any custom manufacturing is that great manufacturing accuracy and precision comes with manufacturing volume, and in the same way low cost and high yield also comes with manufacturing volume. What we mean by this is  'the more you make something, the better you are at it'.

 

If we take the example of custom screen printed electrodes we receive a lot of requests for custom screen printed electrodes, but  when we look at the designs you discover that they are all fairly similar. At ZP we have both standard electrodes and we also provide custom manufacturing services.

 

The benefit of using a ZP standard product, particular our value electrode range, is that they are already a high volume manufacture piece has gone through the wafer mapping process. The advantage to our customers, clients and collaborators is that they can purchase just two electrodes to try out, or thousands of electrodes which have already been functionally tested.


FUNCTIONALIZING ELECTRODES

Zimmer and Peacock is unusual in that we can both manufacture electrodes but we can also functionalize the  electrodes to make them specific; the materials we are used to handling include: aptamers, ionophores, enzymes, DNA antibodies, antigens etc. Zimmer and Peacock has a number or pre-existing sensors and biosensors which can accelerate the time to get to market.


TESTING

At Zimmer and Peacock we are often asked to do custom/contract manufacturing of screen printed electrodes.  At Zimmer and Peacock we take a more holistic approach to the screen printing of electrodes for sensor and biosensor applications.

 

Electrodes on the R and D market are often shipped functionally untested, what this means is that the electrodes are visually inspected but appearance is not a god assessment on how an electrode will function as  a biosensor. ZP is different in that we are able to electrochemically functionally test electrodes and sensors before shipping; at ZP we call this process wafer mapping.

CALIBRATION

ZP can also functionally test electrodes/sensors and so assign calibration factors to the electrodes/sensors so that the performance of the sensor in the hands of the final user is the most precise and accurate it can be.

the calibration factors can be transmitted using technologies such as RFID or QR codes.


MICROFLUIDICS

Self filling/capillary filling is a feature common on glucose electrochemical sensors/strips; at ZP are able to provide this technology either as a custom part or as a standard product; again the use of the standard product reduces tiem and the cost to our collaborators.


If you have any questions regarding ZP please don't hesitate to contact us.

Sat

09

Feb

2019

ZP @ Lab-on-a-Chip 2019 San Diego

ZP will be exhibiting at Lab-on-a-Chip 2019 at San Diego come and see us there.


Sat

09

Feb

2019

ZP @ 71 st AACC 2019 Anaheim CA

ZP will be exhibiting at the AACC in Anaheim, please come and see us there at both 1299.


Sat

09

Feb

2019

ZP @ Sensors 2019 San Jose

ZP will be exhibiting at Sensors 2019 in San Jose, please come and see us there.


Sat

09

Feb

2019

ZP will be at MDDI in Boston 2019

ZP will be exhibiting at MDDI Boston.


Sat

09

Feb

2019

ZP @IFT19 New Orleans

Come and meet ZP at the IFT in New Orleans, we will be exhibiting.


Sat

09

Feb

2019

ZP at ASTA Naples Florida

Zimmer and Peacock will be attending the ASTA conference in Naples Florida, come and see us there.


www.zimmerpeacock.com    2021